Should a 60-year-old woman taper off PPIs for GERD?

Question

Hello doctor,

I am a 60-year-old woman who has been taking proton pump inhibitors (PPIs) for gastroesophageal reflux disease (GERD) for over five years. While the medication effectively controls my symptoms, I am concerned about potential long-term risks, including bone density loss, chronic kidney disease, and nutrient deficiencies such as low magnesium and vitamin B12 levels.

Given these concerns, should I consider tapering off proton pump inhibitors or switching to an alternative treatment like histamine-2 receptor blockers (H2 blockers)? Would you recommend specific tests, such as a bone density scan or blood tests for magnesium, vitamin B12, and kidney function, to monitor my health? Additionally, what strategies can help me manage gastroesophageal reflux disease effectively while minimizing potential long-term risks? Kindly help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

Long-term use of proton pump inhibitors (PPIs) may increase the risk of bone density loss, kidney issues, and nutrient deficiencies.

It may be time to discuss with your doctor whether tapering off PPIs and transitioning to histamine-2 receptor blockers (H2 blockers) or other treatments are appropriate for you.

Lifestyle modifications, such as maintaining a healthy weight, eating smaller meals, and avoiding trigger foods, can also help manage gastroesophageal reflux disease (GERD).

Regular health monitoring is essential—consider a bone density scan and blood tests for magnesium, vitamin B12, and kidney function to detect any potential issues early.

If PPIs remain necessary, use the lowest effective dose and schedule regular checkups to mitigate long-term risks.

I hope this helps.

Revert with the answer to assist further.

Thank you and take care.