Patient's Query
Hello doctor,
I have been dealing with severe asthma for several years and have tried different biological treatments, including Xolair and Dupixent, with limited success. My doctor recently mentioned Tezspire(Tezepelumab) as a new option, but I would like to understand how it compares to other biologics. How does Tezspire work differently from other biological treatments for asthma? I understand that it targets thymic stromal lymphopoietin (TSLP) instead of interleukin-4 (IL-4) or immunoglobulin E (IgE) pathways—does this make it more effective for certain types of asthma? One of my main concerns is how quickly I can expect to see improvement after starting Tezspire. Does it significantly reduce asthma attacks and the need for oral steroids? Additionally, does it help with reducing inflammation and long-term lung function decline? Are there any specific side effects or risks associated with Tezspire that I should be aware of? Lastly, is this treatment only effective for eosinophilic asthma, or can it help patients with other asthma phenotypes as well? I want to make an informed decision before switching to Tezspire, so I would appreciate any insights on its effectiveness and benefits.
Please help.
Thank you.
Hello,
Welcome to icliniq.com.
I understand your concern.
Tezspire (Tezepelumab) treats both allergic and eosinophilic asthma by targeting a molecule called thymic stromal lymphopoietin TLSP (thymic stromal lymphopoietin).Tezspire plays a central role in activating various immune cells, contributing to the pathophysiology of asthma. It prevents TSLP from binding to its receptor and disrupts this in the inflammatory cascade associated with asthma.
Dupixent has an average rating of 7.2 out of 10 from a total of 493 ratings. 61 percent of reviewers reported a positive effect, while 21 percent reported a negative effect. Tezspire has an average rating of 8.7 out of 10 from a total of 34 ratings. There is a 56 percent reduction in asthma attacks compared to people not taking Tezspire.
Tezspire side effects-
Hives.
Back pain.
Injection site reaction.
Sore throat.
Breathing problems.
Red, irritated, or itchy eyes.
Severe dizziness.
I hope this helps.
Kindly follow up if you have more concerns.
Thank you.
The Probable causes
Treatment plan
Same symptoms don't mean you have the same problem. Consult a doctor now!
Related Questions
Is Tezepelumab effective in managing severe asthma?
I have loss of smell and taste with migraine and nasal congestion. Kindly assist.
Asthma During Pregnancy - Signs, Treatment, and Prevention - An Overview
Asthma Triggers: Common Causes and How to Avoid Them
My eosinophil values are high. Does this indicate cancer?
Is Tezepelumab effective for severe asthma?
Ask your health query to a doctor online
*guaranteed answer within 4 hours
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.