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Can oral sex or medications cause white spots on the lips?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am a 19-year-old male. I am scared as I had oral sex three days ago, and I had this white spot inside my bottom lip the next day. I poke it on the outside of the lip, and it hurts sometimes. But it looks like a canker sore. I do not know if it does not hurt unless I touch it, and I was reading that Amoxicillin can cause a canker sore. I took a lot of Amoxicillin because I was ill. I also take Nyquil, Ibuprofen, and a sinus pill. I am hoping I do not have STD. I am just trying to stay positive. I really need your help.

Hello,

Welcome to icliniq.com.

I understand your concern.

I have opened the file, and white patches are clearly visible (attachments are hidden to protect the patient's identity). They seem to be aphthous ulcers, and they can be caused mainly by folic acid deficiency, smoking, and constipation. It could be a canker sore or oral lesions, as in an STD or fungal infection. I suggest you do the following:

  1. Betadine (Povidone iodine) mouthwash after breakfast, lunch, dinner, or after each meal.
  2. Stomela gel (Choline salicylate, Tannic acid, Benzalkonium chloride, and Menthol) is to be locally applied three times a day.
  3. Tablet Fluconazole 150 mg one per day for six days.
  4. Tabet Azithromycin 500mg one per day for six days.
  5. Tablet Stercort (Deflazacort) 6 mg twice after lunch and dinner for six days.
  6. Add citrus fruits like lemon, orange, kiwi, gooseberry, etc to your diet.

You can consult an ENT (ear, nose, throat) specialist also.

I hope this settles your problem.

Feel free to ask if you need.

Regards.

Medically reviewed byiCliniq medical review team

Published At September 13, 2023
Reviewed AtAugust 25, 2025

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