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Does a high lymphocyte count suggest leukemia in a person with familial history?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi,

Should I be concerned that several blood CBC tests over the past two months have been out of range on the high end? Particularly, the absolute lymphocyte count. There is leukemia in my family. I have no symptoms except fatigue and nausea.

Please guide.

Hi,

Welcome to icliniq.com.

I read your query and understand your concern.

Your reports show mild elevated absolute lymphocyte count. But your total WBC (white blood cells) count is normal. So it is not blood cancer.

But if you have had a high absolute lymphocyte count for two months, then we need to be alert and follow the approach for high lymphocyte count as below.

I suggest you investigate with a peripheral blood smear examination.

After the next one to two months, if you still get an absolute lymphocyte count high, then I suggest you investigate with a flow cytometry test to exclude the possibility of monoclonal B-cell lymphocytosis (MBL).

Do not worry about cancer, but follow the approach mentioned above. In addition, I suggest consulting a hematologist nearby for your examination and discussing your reports.

I hope my provided information will be helpful to you.

Let me know if you have more questions in mind.

Best regards.

Medically reviewed byiCliniq medical review team

Published At June 15, 2022
Reviewed AtApril 24, 2026

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