Does Tezepelumab help in the treatment of asthma?

Question

Hello doctor,

My 14-year-old son started Tezspier two months ago for his bad asthma, but he is still having attacks. We were told this shot would make a big difference, but he still needs his inhaler almost daily. Does it take longer to work? Or maybe it is not the right medicine for him? We were really hoping this would help him play sports without worrying about breathing issues all the time.

Please help.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

Tezspire (Tezepelumab) is a relatively new medication approved for severe asthma. It targets thymic stromal lymphopoietin (TSLP), a cytokine involved in airway inflammation.

Time to response:

It is not uncommon for Tezepelumab to take three to six months to show its full effects. However, some patients may experience benefits within the first two to three months.

Factors influencing response:

Several factors can influence the response to Tezepelumab, including:

Severity of asthma: Patients with more severe asthma may require longer treatment durations to achieve optimal benefits.
Comorbidities: The presence of other health conditions, such as allergies or eczema, can impact the response to Tezepelumab.
Adherence to treatment: Consistent administration of Tezepelumab and proper use of inhalers are crucial for optimal benefits.

Next steps:

Consider consulting your son's healthcare provider to discuss the following:

Adjusting treatment plan: The provider may recommend adjusting the treatment plan, such as increasing the dosage or frequency of Tezepelumab.
Adding or modifying other medications: The provider may suggest adding or modifying other medications, such as inhalers or oral medications, to better control asthma symptoms.
Monitoring progress: Regular follow-ups with the healthcare provider will help monitor your son's progress and adjust the treatment plan as needed.

Encouraging sports participation:

While managing asthma symptoms is crucial, it is essential to encourage your son's participation in sports. Discuss the following with his healthcare provider:

Developing an asthma action plan: Create a plan that outlines steps to take before, during, and after sports activities to manage asthma symptoms.
Using inhalers before exercise: Ensure your son uses his inhaler as prescribed before engaging in sports activities.
Monitoring symptoms: Encourage your son to monitor his symptoms and adjust his treatment plan as needed.

I hope this has helped you.

Please feel free to reach me again in case of further queries.

Thank you.