How can I effectively manage a lupus flare-up?

Question

Hello doctor,

I recently had some lab work done, and my results showed that my RBC (5.41), hematocrit (16.4), and hemoglobin (49.9) levels were all flagged as high. For reference, I am a female over 50 years old with preexisting autoimmune conditions. About four months ago, I started experiencing frequent low-grade fevers ranging from 99.3°F to 100.4°F. Since then, I have developed new joint pain (which does not seem related to my lupus), along with increasing hypertension, fatigue, and night sweats.

I should also mention that my mother has chronic lymphocytic leukemia (CLL), and my brother has polycythemia vera. What would be the best next steps for me to take?

Kindly advise.

Thanks.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

Based on the symptoms you have described, including elevated RBC (red blood cell), hematocrit, and hemoglobin levels, persistent low-grade fevers, new joint pain (unrelated to your lupus), increasing hypertension, fatigue, and night sweats combined with significant family history of chronic lymphocytic leukemia (CLL) and polycythemia vera I strongly suspect a possible flare of systemic lupus erythematosus (SLE) or a related autoimmune condition. As a next step, I recommend getting an ANA (antinuclear antibody) test and a Lupus panel, which includes anti-dsDNA and complement levels. Once you have the test results, please share them with me so we can move forward with a clearer picture.

In the meantime, and only after confirming with your local physician, I suggest the following medications: Celecoxib 200 milligrams, to be taken two tablets twice daily for one week; Hydroxychloroquine 100 milligrams to be taken two tablets orally twice daily for three days; and Dexamethasone four milligrams to be taken two tablets orally three times daily for one week.

I hope this information will help you.

Thank you.