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Will Semaglutide impacts fertility?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 34-year-old female. I was prescribed Semaglutide for PCOS-related insulin resistance and weight management. It has helped me lose weight, but I am struggling with nausea and dizziness, which affect my ability to perform and train as a dancer. Are there ways to reduce these side effects while staying active? Also, since I have irregular cycles due to PCOS, could Semaglutide impact my hormones or fertility if I decide to try for a pregnancy in the future?

Please help.

Thank you.

Hello,

Welcome to icliniq.com.

I understand your concern.

Semaglutide can be effective for PCOS (polycystic ovarian syndrome) - related to insulin resistance and weight loss, but nausea and dizziness are common side effects, especially in active individuals like dancers.

How do you reduce nausea and dizziness while staying active?

  1. Eat small, frequent meals – avoid large meals that can worsen nausea.

  2. Stay hydrated – drink plenty of water, especially before and after training.

  3. Avoid greasy or heavy foods – stick to bland, low-fat meals.

  4. Take Semaglutide at night – some people find side effects are less bothersome while sleeping.

  5. Reduce dosage if needed – talk to your doctor about adjusting the dose.

  6. Use ginger or B6 supplements – both may help with nausea.

  7. Gradually increase activity – listen to your body and avoid overexertion.

Impact of Semaglutide on hormones and fertility:

  1. It can improve ovulation– reducing insulin resistance may help regulate cycles.

  2. May increase fertility – weight loss and better hormonal balance can boost the chances of pregnancy.

  3. Should be stopped before pregnancy – Semaglutide is not recommended if trying to conceive, so discuss stopping it when planning pregnancy.

  4. If you are considering pregnancy, your doctor may switch you to Metformin, which also helps with insulin resistance but is safer for pregnancy.

Do you want specific meals or training adjustments to help manage side effects?

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.

Medically reviewed byiCliniq medical review team

Published At April 12, 2025
Reviewed AtApril 12, 2025

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