Can diet and weight management reduce prostate cancer risk?

Question

Hello doctor,

I am 41 years old and recently discovered to have the BRCA2 mutation. My father died of aggressive prostate cancer at 45. My current PSA is 2.8, which is slightly elevated for my age. I have no symptoms, but am experiencing severe anxiety about the risk factors. Recent genetic counseling suggested I am at high risk. I need detailed guidance on screening protocols, preventive measures, and lifestyle modifications. I also have family planning concerns, as my wife wants children. I have a history of anxiety disorder and am taking SSRIs.

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

A BRCA2 (human gene) mutation-positive person will increase the risk of prostate cancer to 15 to 60 percent. Also, it is associated with an increased risk of other cancers, such as pancreatic, breast (7 percent), or melanoma (skin cancer). BRCA 2 prostate cancers are often diagnosed at an early age (below 45), are aggressive, and are more likely to spread beyond the prostate

Prostate cancer screening includes a periodic PSA (prostate-specific antigen) level, digital rectal examination, prostate MRI (magnetic resonance imaging), and biopsy. A health care provider will train you in breast self-examination. Yearly clinical breast examinations and mammograms are recommended.

You should inform your family members that you are BRCA2 positive, as they can consider genetic testing for themselves, as parents, siblings, and children would each have a 50 percent chance of having the same mutation. Also, take note of any close female relatives who were diagnosed with breast cancer before the age of 50, as this could be related to BRCA mutations.

Consult a genetic counselor, who will help you develop a personalized cancer risk management program that may include additional or earlier cancer screening.

Management may be through the BRCA program, which is designed to provide education for men with BRCA mutations, helping them understand the cancer risks and make informed decisions about their health.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.