What are the causes of increased blood cell count?

Question

Hi doctor,

I have done these analyses in CBC, and I need to know the diagnosis. I have a hemoglobin of 17.3 g/dL, RBC of 6.88 million cells/mcL, hematocrit of 51.6 percent, MCV of 75 fL, MCH of 25.1 pg, RDW-CV of 10.9 percent, RDW-SD of 26 fL, MPV of 12.6 fl, and WBC of 3.5 per microliter of blood.

Please help.

Thank you.

Answer 1

Hi,

Welcome to icliniq.com.

I understand your concern. I have gone through the report (attachment removed to protect patient identity), and it is suggestive of polycythemia. The cause of polycythemia can be a primary myeloproliferative neoplasm or secondary polycythemia due to other causes.

To rule out polycythemia, it is necessary to perform a JAK2 (Janus kinase 2) and Exon 12 mutation study using RT-PCR (reverse transcription-polymerase chain reaction). The secondary causes are dehydration, smoking, respiratory causes, cardiac causes, and testosterone levels.

For this, I suggest you investigate chest X-ray and EKG (electrocardiogram) for primary workup. Drink some water and stop smoking if you have the habit. I suggest you investigate serum EPO (erythropoietin). Repeat your CBC (complete blood count) after a few days, and kindly revert with the above-mentioned information. Meanwhile, drink more water and do not forget to revert with repeated CBC after a few days.

I hope this helps.

Thank you.

Answer 2

Hi,

Welcome back to icliniq.com.

The attached chest X-ray does not show any abnormality (attachment removed to protect patient identity), and it seems to be normal. Please mention whether you have a smoking habit. If you have any clinical signs and symptoms, then it is good to mention them in detail to guide you further. Meanwhile, follow the instructions given above.

I hope this helps.

Thank you.