How serious is HR-positive/HER2-negative breast cancer?

Question

Hello doctor,

I have regular yearly checkups to maintain my health. During my last visit, my doctor mentioned HR-positive/HER2-negative breast cancer, but I am not sure what that means.

Should I be concerned about this type of breast cancer?
How does it differ from other types?
Is there anything specific I should be doing during my checkups?
I have heard about various treatments, but I am unsure if it is treatable. What questions should I ask my doctor during my next appointment?

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I went through your query and can understand your concern.

HR-positive breast cancers generally have a better prognosis than HR-negative ones, as hormone-positive cancers tend to grow more slowly and are less aggressive. HR-positive, HER2-negative breast cancers are sometimes referred to as luminal A breast cancers, which often require less aggressive treatment. Sometimes, only surgery and hormonal therapy are required. They typically have an excellent prognosis.

Screening checkups for all types of breast cancer, including this type, usually involve mammography and ultrasound.

The survival rate for patients with HR-positive and HER2-negative breast cancer depends on the stage and molecular profile. In the early stages or up to stage 3, this type of cancer is often curable with proper treatment. Even in stage 4, many patients respond well to treatment, leading to extended survival and improved quality of life.

It is important to note that mammography and biopsy are crucial for confirming HR-positive and HER2-negative breast cancer, as a biopsy is mandatory for an accurate diagnosis.

I hope it helps.

Thanks.