Are atopic dermatitis medicines safe for my pregnancy at 27?

Question

Hello doctor,

I have had atopic dermatitis since childhood, but it has flared up quite badly in the past few months. I have noticed my skin becomes drier and itchier right before my period. I am a 27-year-old and currently trying to conceive. I have been feeling stressed, which seems to worsen my skin. I am using topical steroids and Tacrolimus cream, but I am unsure if these are safe during pregnancy or while breastfeeding. Please tell me;

Can hormonal fluctuations during the menstrual cycle or pregnancy make eczema worse?
Are there any immune or allergy-based treatments that are safe for women planning pregnancy?
Could eczema indicate an overactive immune response that might affect fertility or implantation?
Could stress hormones like cortisol be part of the reason?
Is there any connection between eczema, food intolerances, and fertility outcomes?

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

I understand that it can be difficult with atopic dermatitis, as it is an allergic skin condition. The following factors can cause flare-ups;

Stress.
Hormonal changes.
Lifestyle changes.

It is best to avoid triggers and allergens that cause flare-ups. Certain steroids are considered safe in pregnancy for topical use. But high-dose tropical steroids have limited data. Also, topical Tacrolimus (an immunosuppressive medication) is not associated with any birth-related defects or with any fertility-related issues. But there is again limited data available.

Since you are trying to conceive, I would suggest you have regular visits with your dermatologist for dose modifications. Or you can send your current prescription so that I can suggest the required changes.

Skin allergies generally do not have any connection with fertility, but yes conditions of stress can affect fertility as well as worsen skin allergies.

The following things can be a great help in your allergy

Healthy and balanced diet.
Exercise.
Drink enough fluids during the day.
Stress management.
A proper sleep schedule can help with allergies.

Medications do play a vital role in these conditions, but so does a healthy Lifestyle to prevent flare-ups.

I hope this information helps you.

Feel free to ask further queries.

Thank you.

Are atopic dermatitis medicines safe for my pregnancy at 27?

Atopic Dermatitis and Pregnancy Companion