How serious is autoimmune vasculitis in young women?

Question

Hello doctor,

I married a girl who is 28 years old now. We got married a year ago. She was diagnosed with Wegener's granulomatosis. She is taking medications and injections. I learned about the severity of the disease, so I started feeling low. I am attaching her blood work and reports.

I need to know whether this disease is curable or not. If it is not curable, what challenges can she face?

Kindly suggest.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

I have seen these reports (attachments removed to protect the patient's identity) in the past, also. From these reports, I can say that she is in remission, which means the Wegener's granulomatosis is under control. I understand your concern as the disease is lifelong, and once it is in the remission stage, she will be normal, but relapses can occur.

It is the time when treatment escalation is needed. She is on proper treatment, and her kidney and lung function are normal.

I hope this helps.

Thank you.

Answer 2

Hello,

Welcome back to icliniq.com.

As I said, it is a lifelong disease with no cure. Let me tell you that the tablet Azathioprine is safe during pregnancy. However, Abatacept is a new drug, and as of now, there is limited data on human pregnancy.

Likewise, the tablet Methotrexate is not safe, and so it should be stopped six months before conceiving.

I hope you find this helpful.

Thank you.

Answer 3

Hello,

Welcome back to icliniq.com.

The chances of relapse are there, and no one can predict them. The long-term use of immunosuppressive therapy can result in infections, but they are curable, and vaccination is important to prevent infections. It is a rare disease like diabetes, but it was just an example that there is no cure for either.

I hope this answers your concerns.

Thank you.