Patient's Query
Hello doctor,
I recently did an fluorescent treponemal antibody absorption test (FTA-ABS) test for syphilis. It showed reactive with a titer 1:1. But after a week and a half, I took a venereal disease research laboratory (VDRL) test, and it was non-reactive. Now I am confused. The doctor was not so clear while explaining the difference in the result. Kindly help. Thanks.
Hi,
Welcome to icliniq.com. Thanks for writing in, and I understand your concern. If FTA-ABS (fluorescent treponemal antibody test absorption) test is positive, it will remain positive for lifetime. It suggests that you have been infected with syphilis. It could have been in the past or present. However, VDRL (venereal disease laboratory test) suggests present disease activity. VDRL non-reactive means, at present, infection is not active.
Patient's Query
Hello doctor,
Thank you for the reply. I never had a reactive syphilis test in the past. That is why I am a bit confused. And now, the VDRL is non-reactive after one week of reactive FTA-ABS.
Hello,
Welcome back to icliniq.com. Syphilis is a sexually transmitted disease that is usually a consequence of unprotected sexual activity. venereal disease research laboratory (VDRL) reflects disease activity in syphilis, and titers above 1:8 are considered significant. FTA-ABS test is a specific test that detects antibodies developed against the bacteria after an infection. Hence it remains positive for a lifetime as antibodies are present in the body for the entire life. If you have never been treated for syphilis, you could repeat the VDRL test after four weeks and 12 weeks and check for a rising trend. If increasing, I suggest taking the appropriate antibiotic.
Regards.
Same symptoms don't mean you have the same problem. Consult a doctor now!
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.