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I am taking antihistamines for urticaria; the redness on my skin has disappeared. Can I stop taking the medicines?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have urticaria or hives and have been under antihistamines for five weeks. For the last six days, I had to take a high dose of tablet Fexofenadine Hydrochloride 180 mg four times daily. The redness on my skin has disappeared. Can I stop taking the medicines? If so, should it be done gradually, and how? Please help.

Answered by Dr. Shyam Kalyan N

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

It is not safe to abruptly stop the antihistamines (medications for allergy); the best way is to taper it down gradually. As you take tablet Fexofenadine 180 mg four times daily, make it thrice daily for two days, then twice daily for two days, and once daily for the two consecutive days. Then, make it 120 mg once daily for a week and stop. However, after stopping the antihistamine, wait for a week and do a skin prick test (checks for immediate allergic reactions to many different substances at the same time) as it is important to rule out the cause for urticaria (a skin rash triggered as a response to food, medicines or other irritants). I hope this helps.

Patient's Query

Hi doctor,

Thank you for the reply. I believe it was caused by tablet Ibuprofen, which previously I have had a hives reaction to.

Answered by Dr. Shyam Kalyan N

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

It is good that you have identified the cause, so there is nothing to worry about. Take care. Revert for further queries.

Patient's Query

Hi doctor,

Thank you for the reply. Perhaps I have a few follow-up questions that I need your help on; I was recommended to stop doing sports, having wine, which I occasionally do, and avoiding having high histamine foods during the treatment. Can I start them again? Please guide.

Answered by Dr. Shyam Kalyan N

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

You can start doing sports, and I suggest you have wine occasionally not exceeding one or two glasses, for a few weeks. You may also have foods high in histamine (such as fermented foods, dairy products, avocados, spinach, etc.), but I suggest you start slowly over days. I hope this helps.

Medically reviewed by Dr. K. Shobana
Published At February 18, 2022
Reviewed At May 27, 2026

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

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