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Prednisolone is the only solution for my rectal bleeding. How long can I take it?

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Patient's Query

Hi doctor,

I am a 27-year-old male. For the past five years I have ulcerative colitis. My main problem is bleeding form rectum. When I take Prednisolone, I am fine for maximum of three months and after that again it starts bleeding and also continues with Mesacol.

I also took Azathioprine (Aazoran) but those medicines cannot stop bleeding only Prednisolone is a solution for me what can I do and if I start taking Prednisolone again is that any problem? How many times in a year can I take Prednisolone? In five years, I took Prednisolone for 8-10 times. Please suggest solution.

Kindly help.
Answered by Dr. Arbab Muhammad Kashif Khan

Education:

MBBS

Professional Bio:

Dr. Arbab Muhammad Kashif Khan is a skilled Medical Gastroenterologist specializing in the diagnosis and treatment of digestive and liver disorders. His expertise includes managing conditions such as acid reflux, hepatitis, inflammatory bowel disease, irritable bowel syndrome, and pancreatitis. With a patient-centered and evidence-based approach, Dr. Khan is dedicated to improving gastrointestinal health and enhancing the overall well-being of his patients.

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Hi,

Welcome to icliniq.com.

Your history suggests that you have steroid-dependent ulcerative colitis. So you rightly started Azathioprine (immunosuppressant) and I think it should work if you are taking a proper dose (you have not shared dose of Azoran and your body weight). You can take tablet. Azoran (Azathioprine) as 1.5-2.5 mg per 2.2 lbs body weight. Plus the dose of Mesacol is also low. Increase the dose to at least 2.4 gm/day and you can go up to 4.8 gm/day maximum.

Regarding frequency of steroid dosing, you can take it up to twice per year, in case of flare of your disease, but it will be better to avoid it if you have a better option (Azoran) because steroid has many long term adverse effects.

Thank you.

Medically reviewed by Dr. Vinodhini J.
Published At April 29, 2020
Reviewed At June 15, 2026

Education:

MBBS

Professional Bio:

Dr. Arbab Muhammad Kashif Khan is a skilled Medical Gastroenterologist specializing in the diagnosis and treatment of digestive and liver disorders. His expertise includes managing conditions such as acid reflux, hepatitis, inflammatory bowel disease, irritable bowel syndrome, and pancreatitis. With a patient-centered and evidence-based approach, Dr. Khan is dedicated to improving gastrointestinal health and enhancing the overall well-being of his patients.

This doctor is not available for online consultations on the platform anymore.

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Education:

BDS

Professional Bio:

Dr. Vinodhini J. is a Dental Surgeon with extensive years of clinical experience. She specializes in the diagnosis, prevention, and treatment of dental and oral health issues, including restorative, surgical, and cosmetic procedures. With a patient-centered approach, she focuses on maintaining oral health, alleviating discomfort, and enhancing smiles. Her expertise ensures comprehensive care tailored to each patient’s dental needs and overall wellbeing.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Arbab Muhammad Kashif Khan
Dr. Arbab Muhammad Kashif Khan

Medical Gastroenterology

Education:

MBBS

Professional Bio:

Dr. Arbab Muhammad Kashif Khan is a skilled Medical Gastroenterologist specializing in the diagnosis and treatment of digestive and liver disorders. His expertise includes managing conditions such as acid reflux, hepatitis, inflammatory bowel disease, irritable bowel syndrome, and pancreatitis. With a patient-centered and evidence-based approach, Dr. Khan is dedicated to improving gastrointestinal health and enhancing the overall well-being of his patients.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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