Can a GLP-1 receptor agonist help lower an A1C of 8.2?

Question

Hi doctor,

I am 56 years old and was diagnosed with type 2 diabetes six years ago. I have been managing it with Metformin and diet, but my A1C has recently crept up to 8.2. My doctor suggested starting a GLP-1 receptor agonist.

How do these medications work, and do they also help with weight loss or heart risk?
What should I watch out for with side effects?

Please help me.

Answer 1

Hi,

Welcome to icliniq.com.

I can understand your concern.

GLP-1 agonists work by mimicking the action of a natural hormone called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels and can also affect appetite and digestion. They help the body produce more insulin when needed, reduce the amount of sugar produced by the liver, slow down how quickly food is digested, and can reduce appetite.

When you start taking GLP-1 agonists, you should be closely monitored for potential side effects and cardiovascular events, especially when starting the medication or if you have pre-existing heart conditions.

Common side effects include nausea, vomiting, diarrhea, and constipation, which often subside over time. More serious but less common side effects can include acute gallstone disease, pancreatitis, and allergic reactions.

I hope this answers your questions.

Thank you.