What is combined trisomy risk?

Question

Hello doctor,

I am 12 weeks and three days pregnant, and doctors asked me to double marker test. I have attached my double marker test report. Please check and suggest to me what to do.

Answer 1

Hello,

Welcome to icliniq.com.

I thoroughly read your query and understand your concern.

I saw your attached reports (attachments are hidden to protect the patient's identity). It would be better if you would send me the report in your description of nuchal translucency, family history, and previous obstetric and gynecologist prescriptions,as drug history is missing. Risk is usually calculated on many factors like family history, serum markers, age, and nuchal translucency. If nuchal translucency is less than 2.9, then it is normal, so check this. A family history of anomalies also adds to the risk. Age over 35 years is also considered risky. PAPPA (pregnancy-associated plasma protein A) more than 0.5 MoM (multiple of median) is better, and less than this is not considered normal. Free beta hCG (Human chorionic gonadotropin) Mom 1 is better. Your combined result of risk, which you described, is 1:6967, which means the very least chances or almost negligible, whereas for age, the risk is 1 in 289 chances, which is not more, but age is near the risky age limit. I suggest you have an anomaly scan at 20 weeks, as advised for all pregnancies, to exclude any anomaly.

Hope this helps.

Kind regards.