HomeAnswersFamily PhysicianthyroidAm I losing weight due to any infection or Hashimoto's Thyroiditis?

I have an average weight loss of 4 percent every year. Is it due to any infection?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Sneha Kannan

Published At April 27, 2021
Reviewed AtJune 30, 2023

Patient's Query

Hi doctor,

I am a 36-year-old male. My height is 5 feet 5 inches, and my weight is 125 lbs. I have an average weight loss of 4 percent every year for the last six years. I am eating almost the same way. I am definitely in the stressed-out phase for the previous six years because of a job change and a few personal reasons. I do not know whether that is the reason. Six years back, I shifted to a new room and stayed with few men. After a year, I realized that one of the roommates had been going to the wrong places, which could be the reason for my health issues, and eventually, I moved out. During the stay, that man used to prepare food sometimes, and we used to share things. I do not know if I am overthinking. I noticed that I got allergic to pollen and dust, my weight started to reduce to about 4 percent on average every year. In my recent blood test, I came to know that I have Hashimoto’s Thyroiditis. I also read that infection can cause symptoms like weight loss and autoimmune disorders like Hashimoto’s Thyroiditis. Please let me know if there could be some infection that I need to get checked. If so, please send me the list or details of the tests. In the list of dangerous viral infection tests that I did so far, I have HSV-1 detected. But I read that it is more common.

Hi,

Welcome to icliniq.com.

Thanks for your query.

You have nothing to worry about your health. You do not have to worry about getting any infection from your roommate unless you had sexual exposure with him. Your weight loss is not so significant. It could have been due to some nonspecific factors. But you can do a basic laboratory checkup to rule out the cause.

Tests to do:

1. Hematology and Biochemistry,

a. Blood Tests - CBC (complete blood count).

b. ESR (erythrocyte sedimentation rate).

c. CRP (C-reactive protein), LDH (Lactate Dehydrogenase), HbA1c (Hemoglobin A1c).

d. FBS (fasting blood sugar).

e. PPBS (post prandial blood sugar).

f. Liver function tests- Bilirubin, SGPT (serum glutamic pyruvic transaminase), SGOT (serum glutamic-oxaloacetic transaminase), serum albumin, globulin, albumin/globulin (A/G)ratio.

g. Renal function tests- Serum Creatinine, BUN (blood urea nitrogen), Electrolytes.

h. T3 (triiodothyronine), T4 (tetraiodothyronine), TSH (thyroid stimulating hormone).

i. HIV (human immunodeficiency virus), HCV (Hepatitis C), HBV (Hepatitis B), HSV (Herpes Simplex Virus) and STD (sexually transmitted disease) panel in case of sexual exposure, and COVID-19 antibody.

2. Urine routine.

3. Radiology - X-ray chest.

4. Clinical - blood pressure and ECG (electrocardiogram).

Please revert after tests.

Additionally, please take a protein-based supplement milk drink.

Patient's Query

Thank you doctor,

I did CBC, CMP, some specific parasite test, and autoimmune disorder test. Most of it came normal except TSH and ANA test. I know I have Hashimoto’s Thyroiditis. Can you please check the attached results? CBC and CMP results for the last four years looked similar. Will CBC and CMP results usually show some indication if there is an infection related to bacteria, viruses, or parasites? Does the parasite-related test cover most of the parasites or only a few? Do I have to do any additional parasite tests? I have also tested for Hepatitis A, B, C, HIV, Herpes 1 and 2, chlamydia, gonorrhea, and syphilis. All came negative except HSV-1. I have read that it is common and that it will not cause weight loss. Please correct me if I am wrong.

Hi,

Welcome back to icliniq.com.

Thanks for your query. I saw the attached reports (attachment removed to protect the patient's identity). When were these tests done? I suggest you need thyroid hormone therapy for possible hypothyroidism along with other therapies for thyroiditis. It is best to consult a local endocrinologist for treatment, as you will have to be monitored regularly, and these medicines may not be possible to be prescribed online. Please check and revert.

Patient's Query

Thank you doctor,

These tests were done last week. I am already taking Levothyroxine 25 mcg as per the doctor's prescription. I will consult an endocrinologist. Please let me know if you have inputs for other few questions, which I sent in the previous query.

Hi,

Welcome back to icliniq.com.

A few inputs-

1. HSV-1 - Has the treatment been initiated? Do you have any lesions in either the mouth or genitalia? Extremities or skin?

2. Weight loss- Thyroid disorders could cause loss of weight.

3. Levothyroxine dosage at 25 mcg may be less than optimal.

4. Alternative therapies - Additional alternative agents, for example, monoclonal antibodies may be explored.

5. Reports and Treatments - Kindly send all reports and prescriptions at once. Getting pieces of information in an incomplete manner can hamper me to give you comprehensive advise.

Patient's Query

Hi doctor, Sorry for late response. I was able to complete most of the tests you mentioned. I still see the symptom of weight loss and malabsorption happening. weight dropped from 127 to 121 lbs in this last 1 year. Please help with your inputs Symptoms: 1, Weight loss of 5% each year for last six years. 2, Joint weakness and tiredness. 3, Lesions in genital area comes and goes after applying hydrocortisone cream and comes back. 4, Hands and feet cold most of the times. 5, Every morning runny nose and sneezing even if we avoid allergens like pollen and Dust. 6, Spouse also started loosing weight 5% similarly 7, Fat Malabsorption. Known issues: 1, HSV1, EBV and Hashimoto Thyroiditis positive. Taking levothyroxine for Hypothyroidism and got TSH in standard range Tests done so far that came normal: Blood works - CBC, CMP, TSH, T4 every year, CMV, Quantiferon TB Gold, HSV2, Human-immuno 4th generation, Hep A,B,C, HBA1c, HTLV, CBC with Peripheral Smear, Blood Culture(suboptimal volume), Rheumatoid Factor , C Reactive Protein, ANA Panel, Vitamin D, Vitamin B12, Urine test - Urinalysis with culture, Chlamydia, Gonorrhea, Trichomoniasis, Syphilis, Gastrointestinal - Ova and parasite stool test, Genesis stool test, CT Scan, Chest XRAY, Upper Endoscopy, Colonoscopy, Please help with all below questions 1, Any viral, bacteria, parasite or fungus related infection test that is still missing? or anything that require retesting? 2, Is there a possibility of some secondary infection of liver, pancreas or gallbladder because of some infection? If so, will those miss in CBC or CMP? 3, for blood culture they said suboptimal volume and no growth reported after 5 days and commented saying 'inspection of blood culture bottles indicates that an inadequate volume of blood may have been collected for the detection of sepsis'. Does this mean we need to repeat test? 4, Will blood culture find something after 7 years of possible exposure? 5, Should this require consultation from infectious disease specialist. I see you are also a infectious disease specialist. Please correct me if I am wrong and I need to consult infectious disease specialist. 6, I also see online mentioning about viral culture? Will that be helpful? 7, Any infection that could cause malabsorption?

Hi,

Welcome back to icliniq.com.

1) Epstein-Barr virus (EBV) infection can cause flu-like infection, weight loss, sore throat, enlarged cervical glands, chills, joint pains, nausea, vomiting, rash, and abdominal pain. Most cases are mild and self-limiting, with full recovery occurring over several weeks. There is no specific treatment for EBV. However, some things can be done to help relieve symptoms, including drinking fluids, getting plenty of rest, and taking over-the-counter medications for pain and fever. Some physicians use corticosteroids to treat significant swelling in the throat or an enlarged spleen, but steroids are not needed in most patients. Antiviral medications are available to help oral hairy leukoplakia, including tablet Acyclovir, tablet Ganciclovir and tablet Foscarnet (consult with a specialist doctor, talk with him or her, and take medicine with their consent). In almost all people infected with EBV, the prognosis recover completely in about one to four months. In addition, neurological changes are usually completely resolvable.

2) Herpes simplex virus (HSV) infection shows possible symptoms like tingling, itching, or burning. However, the skin may tingle, itch, or burn before the blisters appear. Sores are generally painful, fluid-filled blisters that break open and ooze fluid and form a crust before healing. Where the sores appear often varies with type:

Oral herpes (HSV-1): Most blisters appear on the lips or around the mouth, the face, and the tongue. Most patients are treated with antiviral medicine, an antiviral cream or ointment that can relieve the burning, itching, or tingling sensation. In addition, oral antiviral pills or intravenous shots can shorten an outbreak of herpes. Antiviral medicines approved for treating both types of herpes simplex include Acyclovir, Famciclovir, and Valacyclovir.

Any virus, bacteria, parasite, or fungus-related infection test that is still missing or anything that requires retesting? - Does not appear that way.

Is there a possibility of some secondary infection of the liver, pancreas, or gallbladder because of some infection? - If so, will those miss incomplete blood count tests. Yes, Secondary bacterial infection may happen. Complete blood count does change in such circumstances.

A blood culture may need to be repeated if the prescriber feels so in his or her clinical judgment since he or she may have had reasons to prescribe the drug.

I cannot prescribe for such diseases. Hashimoto's thyroiditis can cause weight gain. You are already on treatment for its symptoms.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Shubadeep Debabrata Sinha
Dr. Shubadeep Debabrata Sinha

Infectious Diseases

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