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What is the treatment for thalassemia major?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am a thalassemia major patient. My spleen size is 8.2 inch. How to reduce my spleen size? And also I want to increase my weight? I am 21 years old. What percentage of risk is present in an unrelated donor stem cell transplant? My ferritin is 1500 µg/L and weight is 106 lbs. Please suggest some solution.

Answered by Dr. Srivastava Sumit

Education:

MBBS

Professional Bio:

Dr. Sumit Srivastava is a skilled General Practitioner and Family Physician with extensive clinical experience. He is also an expert in Internal Medicine, dedicated to providing comprehensive healthcare for individuals and families. Known for his patient-focused approach, he ensures quality care and long-term wellness. His expertise includes managing lifestyle disorders, chronic illnesses, and preventive healthcare, with a strong emphasis on accurate diagnosis and holistic treatment.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com. At present there is no way to reduce the spleen size. The diet for a thalassemia major patient should include plenty of fruits and vegetables and a protein-rich diet. Taking vitamin C supplements will help to increase the immunity of the body. Bone marrow transplantation is a curative treatment for thalassemia major (symptoms of severe anemia from childhood). Bone marrow transplantation can be done if you do not have any long-term complications of thalassemia major. Adult thalassemia patients are higher-risk patients for transplant-related toxicity due to an advanced phase of disease and have a cure rate of 60 to 70 percent with current treatment protocol. There is a 90 percent long-term survival rate in patients with favorable characteristics such as young age, HLA (human leukocyte antigen) match, and no organ dysfunction. I would suggest you consult a hematologist who can guide you better.

Medically reviewed by Dr. Sneha Kannan
Published At February 15, 2016
Reviewed At January 22, 2026

Education:

MBBS

Professional Bio:

Dr. Sumit Srivastava is a skilled General Practitioner and Family Physician with extensive clinical experience. He is also an expert in Internal Medicine, dedicated to providing comprehensive healthcare for individuals and families. Known for his patient-focused approach, he ensures quality care and long-term wellness. His expertise includes managing lifestyle disorders, chronic illnesses, and preventive healthcare, with a strong emphasis on accurate diagnosis and holistic treatment.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Sneha Kannan is a skilled Dental Surgeon with expertise in providing general dental care, including scaling, fillings, and preventive treatments. She does oral surgery procedures such as extractions and minor surgical interventions. She does procedures in restorative dentistry, including crowns, bridges, and dentures. She is an expert in doing endodontic treatments such as root canal therapy. She is well-versed in doing procedures in cosmetic dentistry, including teeth whitening and smile correction. She can provide pediatric dental care for children’s oral health and preventive treatments. She promotes oral hygiene awareness and preventive dental practices.  

This doctor is not available for online consultations on the platform anymore.

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Education:

MBBS

Professional Bio:

Dr. Sumit Srivastava is a skilled General Practitioner and Family Physician with extensive clinical experience. He is also an expert in Internal Medicine, dedicated to providing comprehensive healthcare for individuals and families. Known for his patient-focused approach, he ensures quality care and long-term wellness. His expertise includes managing lifestyle disorders, chronic illnesses, and preventive healthcare, with a strong emphasis on accurate diagnosis and holistic treatment.

This doctor is not available for online consultations on the platform anymore.

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