Can I take Isotretinoin along with Tetracycline without any drug interaction?

Question

Hi doctor,

I am a 27-year-old female, and I have had mild, cystic acne for the past five years. Yesterday, I got prescribed Accutane 20 mg per day, and my weight is 50 kilograms. If everything is fine, I will be taking it for the next ten months. I know that taking Isotretinoin can cause idiopathic intracranial hypertension and I also take Tetracycline. I have heard that both should not be taken at the same time. I have been taking 100 mg Tetracycline for the past week (seven days). I took my last pill yesterday evening. How long is the wash-out period of Tetracycline? If I take 100 mg Tetracycline per day for seven days, when can I start taking Isotretinoin? Taking after 24 hours is enough?

Answer 1

Hi,

Welcome to icliniq.com.

There should be a time gap of seven days between stopping tetracycline and starting Isotretinoin. Monitor your fasting lipid profile and liver function test. While on Isotretinoin, you should not conceive. There should be a gap of six months after stopping Isotretinoin.

Answer 2

Hi,

Welcome back to icliniq.com.

There are rare case reports showing pseudotumor cerebri.