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Does using Noctiva nasal spray reduce the sodium levels in the body?

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Patient's Query

Hi doctor,

I had a bladder leakage at night. I tested my urine. It was fine. I do not have urine leakage during the daytime. I had this problem for five months. My urologist gave me Nocitva nose spray.

I have read that using Noctiva can lower the sodium present in the body. I tested my sodium level every eight months. It was 142 mEq/L. Do I need to check my sodium level now?

Please suggest.

Thank you.

Answered by Dr. Karthik Rajan

Education:

MCh Urology

Professional Bio:

Dr. Karthik Rajan is an expert in Urology. He is experienced and well-versed in all treatment modalities of Urology.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

Yes, using Noctiva nasal spray (Desmopressin acetate) can cause a decrease in sodium levels in the blood. The risk is small, and it usually happens within the first month. Then your body starts coping with it. Generally, we measure the sodium levels just before starting the drug, a week after starting the medication, and a month after taking the drug. If we find the levels in a stable condition, then we repeat them once every six months.

In your case, as you have started the medication, I would advise you to get a sodium level now and a couple of weeks later. If they are normal, then you can get it done every six months. It is just a precaution to monitor these levels, as the actual risk of developing low sodium levels is less than 10 percent.

I hope this helps.

Kindly revert in case of further queries.

Thank you.

Patient's Query

Hi doctor,

Thank you for the reply.

I had checked the sodium levels every eight months. It was 142 mEq/L.

Will it get changed soon?

Thank you.

Answered by Dr. Karthik Rajan

Education:

MCh Urology

Professional Bio:

Dr. Karthik Rajan is an expert in Urology. He is experienced and well-versed in all treatment modalities of Urology.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

It is not possible to use the sodium levels measured before eight months. Having a recent value measured within a week is necessary. It is a highly reliable value that can change in a matter of hours. Hence, it is better to do testing to know the current value.

If we find that the dosage of the medication does not cause a change in the sodium levels, or if there is no change in the sodium levels, then the sodium levels can be measured at longer intervals.

I hope this helps.

Kindly revert in case of further queries.

Thank you.

Answered by
Medically reviewed by iCliniq medical review team
Published At November 24, 2018
Reviewed At June 16, 2026

Education:

MCh Urology

Professional Bio:

Dr. Karthik Rajan is an expert in Urology. He is experienced and well-versed in all treatment modalities of Urology.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Karthik Rajan

Urology

Education:

MCh Urology

Professional Bio:

Dr. Karthik Rajan is an expert in Urology. He is experienced and well-versed in all treatment modalities of Urology.

This doctor is not available for online consultations on the platform anymore.

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