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Should Semaglutide be stopped if it lowers blood sugar?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am using compounded Semaglutide to try to get my diabetes under better control. It has only been three weeks, but my blood sugar levels have dropped extremely low twice already, which scared me. I am not sure if this is happening because the pharmacy may have made it too strong, or if my diet just needs more adjustment. Also, the packaging did not come with clear instructions, and the label looks a bit faded, to be honest. I have been storing it in the fridge as instructed, but I am wondering if these types of compounded medications can go bad more quickly. I just want to know if I should stop using it or consider switching to a different option.

Kindly help.

Hello,

Welcome to icliniq.com.

I can understand your concern.

Compounded Semaglutide is not approved by the FDA and lacks sufficient information regarding its side effects and the potential severity of those effects. There is currently no formal research available on compounded versions of Semaglutide.

Therefore, it is essential to consult your physician and consider switching to an FDA-approved treatment option. Reported adverse effects of compounded Semaglutide include abdominal pain, constipation, diarrhea, rapid heart rate, and fatigue.

Additionally, poor regulation of blood sugar can lead to episodes of hypoglycemia. If you experience any of these symptoms, they may be related to the compounded medication. It is recommended that you discontinue its use immediately and seek emergency care if you feel unwell.

Potential complications can include low blood pressure, dehydration due to diarrhea, pancreatitis, and liver or kidney issues. You can discuss safer alternatives, such as Wegovy, with your physician. Wegovy is FDA-approved and is backed by ongoing research to monitor both its effectiveness and side effect profile. While cost may be a concern, this should be discussed with your health insurance provider to explore coverage options.

I hope this helps.

Take care.

Answered byDr. Reema Wankar

Medically reviewed byiCliniq medical review team

Published At June 21, 2025
Reviewed AtJune 26, 2025

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