When can blood clots or PE develop?

Question

Hello doctor,

I want to ask

How common is it to develop a blood clot or PE with no underlying clotting disorder, surgery, and not on birth control?
Can a PE happen out of nowhere?
Or is there always a culprit?

Kindly assist.

Answer 1

Hello,

Welcome to icliniq.com.

I have read your query and can understand your concerns.

Usually, there is always an underlying risk factor for the development of deep vein thrombosis. Advanced age, genetic conditions, smoking, obesity, trauma, surgery, etc., are some of the risk factors. Genetic diseases include protein C deficiency, protein S deficiency, prothrombin gene mutation, etc. So it can be ruled out by full coagulation profile testing. Low molecular weight Heparin and oral anticoagulant drugs like Apixaban are the modes of treatment for that. Usually, there is always some risk factor present for PE (pulmonary embolism).

I hope this helps.

Thank you.