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Which pneumococcal vaccine is advised for people with RA?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 36-year-old woman managing rheumatoid arthritis and have been on Adalimumab therapy for over a year. My obstetrician‑gynecologist recently recommended that I receive a pneumococcal vaccine. However, I am a bit uncertain about the different types available, specifically PCV15 and PPSV23. Could you advise on which vaccine is more suitable for individuals on immunosuppressive treatments, such as mine?

Additionally, I am interested in understanding any potential risks associated with these vaccines during pregnancy or while breastfeeding. For context, my most recent white blood cell count was 3.8, and I frequently experience sinus infections.

Please help.

Thank you.

Hi,

Welcome to icliniq.com.

I completely understand your concerns.

I am here to support you every step of the way. Regarding your inquiry about pneumococcal vaccination (pneumococcal disease is caused by the bacterium Streptococcus pneumoniae, meaning it can show up as anything from a simple ear or sinus infection to more serious conditions like pneumonia, bacterial bloodstream infections, or meningitis) for women on immunosuppressive therapy (immunosuppressive therapy uses medications or treatments to reduce the strength of the immune system):

Here is the recommended schedule for strong protection:

  • PCV13: Administered first to build a solid immune response.

  • PPSV23: Given at least eight weeks after PCV13.

  • Second Dose of PPSV23: Sometimes advised five years after the first for women with ongoing immune suppression.

You will be relieved to know that both PCV13 and PPSV23 are considered safe during pregnancy and breastfeeding. While the data are limited, there is no evidence suggesting any harm to your baby.

Please continue your regular gynecological consultations; they are a key part of ensuring both your health and peace of mind.

To help me tailor my recommendations just for you, could you please let me know:

  1. Have you experienced any of these symptoms for more than 15 days: fever with chills, shortness of breath, or a persistent cough?

  2. Do you feel any neck stiffness?

Your answers are so valuable in helping me determine the best next steps for your care.

I hope this helps.

Kindly revert if there is any query.

Thank you.

Medically reviewed byiCliniq medical review team

Published At September 15, 2025
Reviewed AtSeptember 15, 2025

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