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Suffering from PCOD and taking medicines, but still it has not reduced. Can you help ?

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Patient's Query

Dear Doctor,

  • I am a 29 year old female suffering from PCOD, taking medicines from past 1 year. But still it has not reduced. I was into Metformin and Folic acid. At the same time I have also taken medicines for conception (i.e, clomiphene).
  • Follicar study has been conducted for four times and only once the egg ruptured, but I did not conceive.
  • From december onwards the follicles are not maturing upto required level.
  • Again during February and March my doctor put me on K-35 as my periods during past 1 year were not regular and still are irregular (I have to take tablet Norgest thrice daily for 5 days and then periods come).
  • Recently I have consulted another doctor, she has prescribed me to stop taking Metformin and instead to start on APCOD sachet (Myo-inositol) and Safegest D (dehydroepiandrosterone) and during periods Adova (Anastrozole).

But I have not yet started the medicines. I am a bit confused, whether should I totally stop Metformin and start with these new drugs?

Answered by Dr. Richa Agarwal

Education:

MBBS

Professional Bio:

Dr. Richa Agarwal is an Obstetrician and Gynecologist with 26 years of clinical experience. She completed her MBBS and DGO at the Rani Durgavati Vishwavidyalaya. She treats health issues in women during and after pregnancy and is concerned with the fetus's health. Currently, she is practicing in Gurgaon, Haryana, India.

This doctor is not available for online consultations on the platform anymore.

Hi, Welcome to icliniq.com.

Metformin is a very effective medicine in PCOD (Polycystic Ovarian Disease) treatment.

It reduces weight, increases sensitivity to insulin and decreases androgen level.

All these effects are helpful in the treatment of PCOD.

But as you say it is not effective in your case; you can start these above mentioned medications instead of metformin.

But use of myo-inositol in PCOD is not very clear.

You should consult an expert gynaecologist for your treatment. If you have further questions, feel free to ask an obstetrician and gynaecologist online.

Medically reviewed by iCliniq medical review team
Published At July 28, 2018
Reviewed At May 7, 2025

Education:

MBBS

Professional Bio:

Dr. Richa Agarwal is an Obstetrician and Gynecologist with 26 years of clinical experience. She completed her MBBS and DGO at the Rani Durgavati Vishwavidyalaya. She treats health issues in women during and after pregnancy and is concerned with the fetus's health. Currently, she is practicing in Gurgaon, Haryana, India.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

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Education:

MBBS

Professional Bio:

Dr. Richa Agarwal is an Obstetrician and Gynecologist with 26 years of clinical experience. She completed her MBBS and DGO at the Rani Durgavati Vishwavidyalaya. She treats health issues in women during and after pregnancy and is concerned with the fetus's health. Currently, she is practicing in Gurgaon, Haryana, India.

This doctor is not available for online consultations on the platform anymore.

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