iCliniq Logo
HomeAnswersInternal Medicinenosebleeds

Does Accutane cause severe bleeding from nose?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have been using Accutane for seven months. I am currently in the last two weeks of my last round of treatment. In the past one and a half weeks, I have been experiencing relatively bad headaches that have not gotten any worse.

Yesterday, I experienced a severe nosebleed that lasted for about two minutes. Pretty quickly after stopping the first nosebleed, I experienced a second nosebleed that resulted in me pulling a blood clot out of my nose that was approximately 0.9 inches long and 0.8 inches wide.

My concern is that I am running a half-marathon in two days, and I am unsure of whether I should go through with this or let my body rest.

Please advise.

Thank you.

Hello,

Welcome to icliniq.com.

Nosebleeds are a known side effect of Isotretinoin, but fortunately, they often resolve quickly after discontinuing the medication. Considering your upcoming marathon in two days, I recommend temporarily stopping the tablet. It is also essential to have your blood pressure checked, as Isotretinoin can potentially cause an increase in blood pressure.

However, there's no need to worry too much about the nosebleed (caused by a blood clot), as marathons typically have paramedic teams that can provide assistance if needed. Enjoy your life and go ahead with the marathon, and I wish you the best of luck!

I hope this helps.

Thank you.

Medically reviewed byiCliniq medical review team

Published At September 26, 2016
Reviewed AtFebruary 24, 2026

Same symptoms don't mean you have the same problem. Consult a doctor now!

Listen to related tracks in our music library

Read answers about:

nosebleedsisotretinoin

Ask your health query to a doctor online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.