Patient's Query
Hello doctor,
I have Crohn's disease and am now hit with norovirus. Vomiting and diarrhea are worse than my worst Crohn's flare. I cannot keep my Crohn's medicines down (on Humira and Azathioprine). I am missing doses. I have severe abdominal pain - cannot tell if it is due to a virus or Crohn's flaring from missed medicines. I am getting dehydrated fast. Already had two hospitalizations this year for Crohn's. Is this virus more dangerous for me? Should I go to the hospital? I am worried that my immunosuppressants make this condition more serious. How do I know if this is triggering a major Crohn's flare?
Kindly help.
Hello,
Welcome to icliniq.com.
I read your query and can understand your concern.
I want some information. Kindly answer the following few questions:
Norovirus infection is a self-limiting infection, lasting for 4 to 5 days, which needs treatment for symptoms only. But, norovirus can have severe symptoms if you have Crohn's disease or any other form of irritable bowel syndrome (IBS).
Generally, immunosuppressants are given for Crohn's disease. However, these immunosuppressants can cause a flare-up of any gastrointestinal tract (GIT) infection. Hence, you must consult with your GI specialist and drop this dose of immunosuppressant - Injection Humira (Adalimumab) (tumor necrosis factor blocker) and Azathioprine (immunosuppressant).
Dehydration is the main concern for norovirus infection. Dehydration could be serious if water intake is not maintained.
Signs of severe dehydration include:
Pale and sunken eyes.
Cold hands or feet.
Faster breathing and heart rate.
Irritability, drowsiness, or confusion.
Dark yellow pee or less frequent urination.
Reduced skin elasticity.
If any of these signs are seen, please go to the emergency room (ER).
Symptoms must subside within four to five days. Due to Crohn's disease, you might have a prolonged recovery of up to 10 to 12 days. If you notice any intermittent diarrhea after the complete remission of current norovirus symptoms, then it could be post-infection IBS. If you notice such episodes, kindly consult your GI specialist for further management.
I advise you to do the following:
Antiemetics like the tablet Ondem for vomiting.
Imodium (antidiarrheal) for diarrhea.
Antispasmodics like Cyclopam (Dicyclomine and Paracetamol).
Yogurt can help maintain normal gut flora if well tolerated by your gut.
Multivitamin supplements after consulting a gastrointestinal (GI) specialist.
Norovirus infection can seriously affect the patient of Crohn's disease. But the norovirus infection generally do not have long term effects on the digestive system. Symptoms may be severe but recover fully in majority of patients.
The probable cause may be norovirus infection.
Kindly consult a specialist doctor, talk with them, and take proper guidance.
I hope this helps.
Thank you.
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Answered byDr. Reema Wankar
Medically reviewed byiCliniq medical review team
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