HomeAnswersHIV/AIDS specialistnimesulide

Does Nimesulide impact PEP or HIV treatment success?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am on a post-exposure prophylaxis. Today is the eighth day. Today I was diagnosed with tonsillitis. The doctor told me to take Nimesulide. Does it make HIV (Human Immunodeficiency Virus) treatment fail? Please, help me.

Answered by Dr. Rakesh Kumar Bahunuthula

Education:

MD

Professional Bio:

Dr. Rakesh Kumar Bahunuthula is a well-experienced Dermatologist, Cosmetologist, and Hair Transplant Surgeon. He is skilled in treating a wide range of skin, hair, and cosmetic concerns, including acne, pigmentation, aging-related changes, and skin disorders. Dr. Bahunuthula specializes in advanced hair restoration techniques, aesthetic procedures, laser treatments, and minimally invasive cosmetic solutions. He emphasizes personalized care, natural-looking results, and improving patients’ confidence and overall appearance.

This doctor is not available for online consultations on the platform anymore.

Hi, Welcome to icliniq.com.

It depends upon what drugs you have been given as post-exposure prophylaxis. Nimesulide does have a few drug interactions although not to the extent of causing drug failure. Kindly mention the drugs you are using for PEP(Post-exposure prophylaxis).

I hope I have answered your question.

Let me know if I can assist you further.

Thank you.

Patient's Query

Thank you doctor,

These are the drugs I am taking. Tenofovir Fumarato desoproxila, Lamivudina (300 mg each), Norvir, Ritonavir 100 mg, Atazanavir sulfate 300 mg.

Answered by Dr. Rakesh Kumar Bahunuthula

Education:

MD

Professional Bio:

Dr. Rakesh Kumar Bahunuthula is a well-experienced Dermatologist, Cosmetologist, and Hair Transplant Surgeon. He is skilled in treating a wide range of skin, hair, and cosmetic concerns, including acne, pigmentation, aging-related changes, and skin disorders. Dr. Bahunuthula specializes in advanced hair restoration techniques, aesthetic procedures, laser treatments, and minimally invasive cosmetic solutions. He emphasizes personalized care, natural-looking results, and improving patients’ confidence and overall appearance.

This doctor is not available for online consultations on the platform anymore.

Hi, Welcome back to icliniq.com.

Thanks for mentioning the drugs used. Nimesulide is a banned drug in many countries all over the world, in view of its serious side effects on the liver. In combination with post-exposure prophylaxis, the risk for side effects does increase further. Although the drug does not affect the efficacy of the other anti-HIV medicines, it is not advisable for use together in view of combined effects on the liver. There are many easily available alternatives for Nimesulide, such as Paracetamol or Diclofenac, which are safer and can be used together with PEP medication.

I hope I have answered your question.

Let me know if I can assist you further.

Thank you.

Medically reviewed by iCliniq medical review team
Published At May 19, 2017
Reviewed At December 18, 2025

Education:

MD

Professional Bio:

Dr. Rakesh Kumar Bahunuthula is a well-experienced Dermatologist, Cosmetologist, and Hair Transplant Surgeon. He is skilled in treating a wide range of skin, hair, and cosmetic concerns, including acne, pigmentation, aging-related changes, and skin disorders. Dr. Bahunuthula specializes in advanced hair restoration techniques, aesthetic procedures, laser treatments, and minimally invasive cosmetic solutions. He emphasizes personalized care, natural-looking results, and improving patients’ confidence and overall appearance.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Rakesh Kumar Bahunuthula is a well-experienced Dermatologist, Cosmetologist, and Hair Transplant Surgeon. He is skilled in treating a wide range of skin, hair, and cosmetic concerns, including acne, pigmentation, aging-related changes, and skin disorders. Dr. Bahunuthula specializes in advanced hair restoration techniques, aesthetic procedures, laser treatments, and minimally invasive cosmetic solutions. He emphasizes personalized care, natural-looking results, and improving patients’ confidence and overall appearance.

This doctor is not available for online consultations on the platform anymore.

Listen to related tracks in our music library
Comprehensive Second Opinion

Read answers about:

post-exposure prophylaxisnimesulide

Ask your health query to a doctor online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.