How to treat hypopigmented mycosis fungoides?

Question

Hi doctor,

A 9-year-old girl's biopsy report reads like this. I would like to know the cause and treatment. Biopsy shows sparse superficial perivascular infiltrate of lymphocytes. The epidermis shows slight psoriasiform hyperplasia and infiltration by numerous small and large lymphocytes without much spongiosis.

Several lymphocytes are aligned along the basal layer in a toy soldier pattern. There is no granuloma, nor is there any infiltrate around arrector pilorum muscles or nerves. Impression—hypopigmented mycosis fungoides (patch stage).

Kindly help.

Answer 1

Hi,

Welcome to icliniq.com.

Mycosis fungoides is a type of cutaneous T-cell lymphoma, characterized by the abnormal proliferation of T cells in the skin. As such, there is no well-defined cause. An interplay of various factors causes it. There are aberrations in the chromosomes triggered by a persistent antigen due to an infection or environmental factor.

And treatment is based on the stage or extent of the disease. The patch stage is the initial stage of presentation. For the localized disease, various options are available, like surgical removal of the lesions, intralesional injections of steroids or topical steroids, or phototherapy. However, I advise you to consult your dermatologist and undergo regular treatment under their supervision.

Thanks.