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Is inherited MTHFR mutation a risk factor for breast cancer?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I need help to understand the attached breast ultrasoud. I also have the MTHFR gene mutation inherited from both parents and want to know if it will affect my lymphocyte count to be high. I am taking Maxalt for migraines.
Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

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Hi,

Welcome to icliniq.com.

I have seen the attached report (attachment removed to protect patient identity).

MTHFR gene mutation is not an independent risk factor for breast carcinoma. The association between this gene mutation and breast malignancy is not fully understood. However, in your attached ultrasound, breast mass is not present. There is no malignant mass in the breast in the ultrasound report. So do not worry about breast cancer.

But if the mentioned nodule and enlarged lymph node persist for a few days, then biopsy can be taken for histopathology examination. Histopathology examination will be the best to diagnose the exact cause for that nodule and enlarged node. As far as the ultrasound report is concerned, do not worry about that.

Lymphocytes are mildly elevated. It could be due to viral inflammation as well. Repeat your CBC (complete blood count) after a few days and revert back.

I hope this helps.

Medically reviewed by Dr. Vinodhini J.
Published At July 30, 2020
Reviewed At July 4, 2024

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. Vinodhini J. is a Dental Surgeon with extensive years of clinical experience. She specializes in the diagnosis, prevention, and treatment of dental and oral health issues, including restorative, surgical, and cosmetic procedures. With a patient-centered approach, she focuses on maintaining oral health, alleviating discomfort, and enhancing smiles. Her expertise ensures comprehensive care tailored to each patient’s dental needs and overall wellbeing.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri

Pathology

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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