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Can Progesterone injection cause miscarriage?

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Patient's Query

Hi doctor,

I had three miscarriages after taking a Progesterone injection. The two miscarriages were chemical pregnancy and the other one was formed. But miscarriage happened. Now I am having pregnancy symptoms. My last menstrual period was 40 days back.

Answered by Dr. Sravanthi Nuthalapati

Education:

MBBS

Professional Bio:

Dr. Sravanthi Nuthalapati is a skilled and compassionate Obstetrician and Gynecologist. Her expertise includes high-risk pregnancy management, infertility evaluation, menstrual disorder treatment, PCOS management, and comprehensive prenatal and postnatal care. She is also well-versed in minimally invasive gynecological procedures and is committed to providing personalized and evidence-based care for women’s health at every stage of life.

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Hi,

Welcome to icliniq.com.

Based on your obstetric history, it is necessary to evaluate the cause of having a recurrent miscarriage. Progesterone injection will not cause any miscarriage as progesterone is the hormone necessary for the continuation of pregnancy and it acts as a support for pregnancy. The common causes of recurrent miscarriage are thyroid abnormalities or impaired blood glucose level or sometimes immune causes like APLA (antiphospholipid antibodies) syndrome. According to your LMP (last menstrual period), you are exactly six weeks pregnant, and do a scan to check whether it is a viable pregnancy. If it is viable, you can start taking Progesterone in the form of oral supplements to sustain pregnancy. You need to undergo some blood tests to look for any abnormalities other than antenatal investigations.

Investigations to be done

You need to do blood group and Rh (rhesus) typing, complete hemogram, Hb (hemoglobin) electrophoresis, urine routine and microscopy, LFT (liver function test), RFT (renal function test), 75-gram oral glucose tolerance test, Hba1c (hemoglobin a1c), HIV (human immunodeficiency virus), VDRL (venereal disease research laboratory test), HbsAg (hepatitis B surface antigen), anti-HCV (anti-hepatitis virus C) and APLA (antiphospholipid antibodies) workup. It includes lupus anticoagulant, beta 2 glycoprotein IgG (immunoglobulin G) and IgM (immunoglobulin M), and anti-cardiolipin antibodies IgG and IgM. You need to do an NT (nuchal translucency) scan (11 to 13 weeks), dual marker test (11 to 13 weeks), and level 2 scan (18 to 20 weeks) to look for any structural or developmental abnormalities in the fetus.

Treatment plan

Take Progesterone supplements after checking viability and low dose aspirin or heparin can be taken after doing an ultrasound for viability and blood test evaluation.

Preventive measures

Avoid having intercourse in the first trimester and take small meals at frequent intervals to avoid having nausea or bloating.
Medically reviewed by Dr. Sneha Kannan
Published At April 20, 2020
Reviewed At January 30, 2024

Education:

MBBS

Professional Bio:

Dr. Sravanthi Nuthalapati is a skilled and compassionate Obstetrician and Gynecologist. Her expertise includes high-risk pregnancy management, infertility evaluation, menstrual disorder treatment, PCOS management, and comprehensive prenatal and postnatal care. She is also well-versed in minimally invasive gynecological procedures and is committed to providing personalized and evidence-based care for women’s health at every stage of life.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. Sneha Kannan is a skilled Dental Surgeon with expertise in providing general dental care, including scaling, fillings, and preventive treatments. She does oral surgery procedures such as extractions and minor surgical interventions. She does procedures in restorative dentistry, including crowns, bridges, and dentures. She is an expert in doing endodontic treatments such as root canal therapy. She is well-versed in doing procedures in cosmetic dentistry, including teeth whitening and smile correction. She can provide pediatric dental care for children’s oral health and preventive treatments. She promotes oral hygiene awareness and preventive dental practices.  

This doctor is not available for online consultations on the platform anymore.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Sravanthi Nuthalapati
Dr. Sravanthi Nuthalapati

Obstetrics and Gynecology

Consult this doctor

Education:

MBBS

Professional Bio:

Dr. Sravanthi Nuthalapati is a skilled and compassionate Obstetrician and Gynecologist. Her expertise includes high-risk pregnancy management, infertility evaluation, menstrual disorder treatment, PCOS management, and comprehensive prenatal and postnatal care. She is also well-versed in minimally invasive gynecological procedures and is committed to providing personalized and evidence-based care for women’s health at every stage of life.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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