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What treatment would you recommend for endometrial hyperplasia?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

Would you be kind to give us a second opinion based on attached files? Please find the attached pathology report of my wife where basically she was given two options. I have uploaded the findings of endometrial hyperplasia. The options given are hormones for life, Progesterone with three to four months checkup and follow ups and hysterectomy.
Answered by Dr. Ajit Naniksingh Kukreja

Education:

MBBS

Professional Bio:

Dr. Ajit Naniksingh Kukreja is a General Surgeon with expertise in performing a wide range of surgical procedures and managing pre- and post-operative care. He is an expert in the diagnosis and surgical management of abdominal, gastrointestinal, and soft tissue conditions. He does emergency surgeries, including trauma and acute abdominal cases. He is an expert in managing hernia, appendectomy, and gallbladder surgeries. He also does preoperative assessment and postoperative care.

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Hi,

Welcome to icliniq.com.

I have gone through the reports and the history of illness provided (attachment removed to protect patient identity).

  • Considering the fact that the submucosal fibroid is quiet small in size and the histopathology is suggestive of proliferative endometrium, it is advisable that the patient goes for hormones.
  • On the other hand, considering the age, having crossed the fertile age and hormones having its inherent issues hysterectomy is advised.
  • Now coming to my impression, given a choice to decide as a medical practitioner, I would opt for hysterectomy.

For further information consult a medical oncologist online.

Patient's Query

Thank you doctor,

We have a few follow up questions. If we opt for a hormonal therapy for time being, then what is the first line hormone therapy medicine available? Is there vaginal cream hormone medicine available? The doctor here put her in category 10, which is a definite diagnosis of cancer. Second, is there assurance with hormonal therapy that endometrial hyperplasia will not allow in good percentage progression to full blown cancer in a short period of time? How often checkups are done using hormonal therapy? Would you ever recommend any other option beside the two mentioned? I tend to be very wary about homeopathy or similar pseudo science treatment options. Would you agree?

Answered by Dr. Ajit Naniksingh Kukreja

Education:

MBBS

Professional Bio:

Dr. Ajit Naniksingh Kukreja is a General Surgeon with expertise in performing a wide range of surgical procedures and managing pre- and post-operative care. He is an expert in the diagnosis and surgical management of abdominal, gastrointestinal, and soft tissue conditions. He does emergency surgeries, including trauma and acute abdominal cases. He is an expert in managing hernia, appendectomy, and gallbladder surgeries. He also does preoperative assessment and postoperative care.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Hi,

Welcome back to icliniq.com.

  • Progesterone is available in oral, injectable and intrauterine device forms.
  • Yes, it all depends on the presence of atypia or in simple words deformed abnormal cells and 10 means complex with atypia.
  • In simple hyperplasia without atypical cells, it is unlikely that it will go for acute transformation into malignancy.
  • We prefer repeat examination every three months. If there is no response for six months, hysterectomy should be opted and if there is a response, then the medicine should be continued for 12 months.
  • These are the two time tested modalities of treatment. We prefer not to comment on alternative forms of medicine.
  • As mentioned, if no response after six months, then go ahead with hysterectomy.

For further information consult a medical oncologist online.

Medically reviewed by iCliniq medical review team
Published At August 9, 2016
Reviewed At April 13, 2025

Education:

MBBS

Professional Bio:

Dr. Ajit Naniksingh Kukreja is a General Surgeon with expertise in performing a wide range of surgical procedures and managing pre- and post-operative care. He is an expert in the diagnosis and surgical management of abdominal, gastrointestinal, and soft tissue conditions. He does emergency surgeries, including trauma and acute abdominal cases. He is an expert in managing hernia, appendectomy, and gallbladder surgeries. He also does preoperative assessment and postoperative care.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

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Decision Helper
Endometrial Hyperplasia Treatment Decision Helper

Considering treatment for endometrial hyperplasia?

This tool helps you weigh options for endometrial hyperplasia based on key factors from your medical situation.

  • Understand factors influencing treatment choices.
  • Explore options like hormonal therapy and hysterectomy.
  • Prepare questions for your doctor.

For guidance only, not a diagnosis. Always consult a healthcare professional. Medications should be taken after consulting a physician. The dosages will be prescribed by the physician. Do not alter, start, or stop medications without consulting a healthcare professional.
Dr. Ajit Naniksingh Kukreja
Dr. Ajit Naniksingh Kukreja

Medical Gastroenterology

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Education:

MBBS

Professional Bio:

Dr. Ajit Naniksingh Kukreja is a General Surgeon with expertise in performing a wide range of surgical procedures and managing pre- and post-operative care. He is an expert in the diagnosis and surgical management of abdominal, gastrointestinal, and soft tissue conditions. He does emergency surgeries, including trauma and acute abdominal cases. He is an expert in managing hernia, appendectomy, and gallbladder surgeries. He also does preoperative assessment and postoperative care.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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