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Is immunotherapy effective for my wife’s PD-L1 lung cancer?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My wife has lung cancer, PD-L1. I need your advice regarding the continuation of this therapy. Docetaxel and Nintedanib are suggested. I think it is too heavy. I would prefer immunotherapy for her PD-L1 lung cancer if possible.

Kindly help.
Answered by Dr. Kumar Varadarajan Senthil

Education:

MBBS

Professional Bio:

Dr. Kumar Varadarajan Senthil is a Medical Oncologist specializing in Radiation Oncology. He is an expert in advanced radiation therapy techniques such as IMRT, IGRT, and stereotactic radiosurgery. He does Multimodal cancer treatment planning in collaboration with surgical and medical oncology teams. He helps in the management of solid tumors, including lung, head and neck, breast, and prostate cancers. He can also give symptom control, palliative care, and quality-of-life improvement for cancer patients. He can do precision oncology and treatment personalization based on genetic and molecular profiling. He also does research in radiobiology and clinical trials for innovative cancer therapies.

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Hi,

Welcome to icliniq.com.

I would suggest going with the Abraxane or Avastin plus Nivolumab combination for the following reasons:

  1. Using immunotherapy now, as you do not want to miss the window of opportunity.
  2. Being targeted agents, side effects are not going to be a major issue compared to conventional chemotherapy drugs.
  3. In my personal experience, Docetaxel in the second-line setting is too much for patients, and quality of life takes a bit of a hit.
  4. Targeting VEGF and PD1, plus Abraxane, gives the best possible chance for an optimal outcome.

I hope this information helps you.

Feel free to reach out in case of further queries.

Thank you.

Medically reviewed by Dr. K. Shobana
Published At June 10, 2018
Reviewed At April 2, 2026

Education:

MBBS

Professional Bio:

Dr. Kumar Varadarajan Senthil is a Medical Oncologist specializing in Radiation Oncology. He is an expert in advanced radiation therapy techniques such as IMRT, IGRT, and stereotactic radiosurgery. He does Multimodal cancer treatment planning in collaboration with surgical and medical oncology teams. He helps in the management of solid tumors, including lung, head and neck, breast, and prostate cancers. He can also give symptom control, palliative care, and quality-of-life improvement for cancer patients. He can do precision oncology and treatment personalization based on genetic and molecular profiling. He also does research in radiobiology and clinical trials for innovative cancer therapies.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Kumar Varadarajan Senthil
Dr. Kumar Varadarajan Senthil

Radiation Oncology

Consult this doctor

Education:

MBBS

Professional Bio:

Dr. Kumar Varadarajan Senthil is a Medical Oncologist specializing in Radiation Oncology. He is an expert in advanced radiation therapy techniques such as IMRT, IGRT, and stereotactic radiosurgery. He does Multimodal cancer treatment planning in collaboration with surgical and medical oncology teams. He helps in the management of solid tumors, including lung, head and neck, breast, and prostate cancers. He can also give symptom control, palliative care, and quality-of-life improvement for cancer patients. He can do precision oncology and treatment personalization based on genetic and molecular profiling. He also does research in radiobiology and clinical trials for innovative cancer therapies.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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