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Is immunotherapy effective for my wife’s PD-L1 lung cancer?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My wife has lung cancer, PD-L1. I need your advice regarding the continuation of this therapy. Docetaxel and Nintedanib are suggested. I think it is too heavy. I would prefer immunotherapy for her PD-L1 lung cancer if possible.

Kindly help.

Answered by Dr. Kumar Varadarajan Senthil

Hi,

Welcome to icliniq.com.

I would suggest going with the Abraxane or Avastin plus Nivolumab combination for the following reasons:

  1. Using immunotherapy now, as you do not want to miss the window of opportunity.
  2. Being targeted agents, side effects are not going to be a major issue compared to conventional chemotherapy drugs.
  3. In my personal experience, Docetaxel in the second-line setting is too much for patients, and quality of life takes a bit of a hit.
  4. Targeting VEGF and PD1, plus Abraxane, gives the best possible chance for an optimal outcome.

I hope this information helps you.

Feel free to reach out in case of further queries.

Thank you.

Answered byDr. Kumar Varadarajan Senthil

Medically reviewed byDr. K. Shobana

Published At June 10, 2018
Reviewed AtApril 2, 2026

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Kumar Varadarajan Senthil
Dr. Kumar Varadarajan Senthil

Radiation Oncology

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