What may be the reason for low white blood count and elevated lymphocytes?

Hello,

Welcome to icliniq.com.

Following is my opinion on your question.

In your attached reports (attachment removed to protect the patient's identity), the only notable finding is mild leukopenia, which means low white blood cell (WBC) count. There are many causes for low WBC count, like an autoimmune disorder, cancer, infections like HIV (human immunodeficiency virus) and TB (tuberculosis), etc.

But sometimes, without any apparent cause, the WBC count can also come low. In the attached report, the lymphocyte count was also normal. You might have a temporary infection or inflammation that has suppressed the bone marrow, thus reflecting a low WBC count. All other parameters are within the limit. So you need not worry about a low WBC count.

Your peripheral smear also shows normal white blood cell morphology. So there is no possibility of cancer as well. I suggest you monitor your WBC count after a few weeks. If lymphocytes are increasing or if the WBC count is going low, then flow cytometry (to analyze the chemical and physical characteristics of the cell) can be planned in the future.

You can visit a nearby hematologist for your physical examination and discuss all these.

I hope I have answered your question. Let me know if you have more questions in mind.

Best regards.

Hello,

Welcome back to icliniq.com.

Following is my opinion on your questions. From the attached reports (attachment removed to protect the patient's identity), your red blood cells show anisopoikilocytosis and polychromasia.

Anisocytosis means variations in the size of red blood cells. Poikilocytosis means variations in the shape of red blood cells. These two findings are significant only when the hemoglobin level is low. Low hemoglobin is suggestive of anemia, in which anisopoikilocytosis is increased. But in your case, the hemoglobin level is average, so anisopoikilocytosis is not a matter of concern in your CBC (complete blood count).

Polychromasia means a bluish tinge in red blood cells, which is seen in the case of red blood cell destruction, like hemolytic anemia. In your case, hemoglobin, LDH (lactate dehydrogenase), and retic count (reticulocyte count) are normal. So you can neglect polychromasia findings as well. Therefore, in your case, anisopoikilocytosis and polychromasia are not a matter of concern, and they do not suggest any dangerous hematological condition. Your hepatitis report is also negative. So you do not need to worry about hepatitis infection.

I hope I have answered your question. Let me know if I can assist you further.

Best regards.