Can gastric problems lower the WBC level and ANC?

Question

Hello doctor,

I recently got my blood test done, and the reports showed neutrophils were 0.4 neutrophils/mcL, and WBC were 3000 WBC/mL. My doctor suggested a repeat of the blood tests within three days and also asked me to get tested for a number of inflammatory diseases like celiac disease. My blood test reports showed an increased neutrophil count to 1.9 neutrophils/mcL and WBC to 4000 WBC/mL. Also, I have had a history of gastric issues like bloating, constipation, and mild gastritis for the past 15 years. I have got a colonoscopy and endoscopy done, and the reports were normal. I am an active individual. My heart rate stays around 100 beats per minute. I have also got an EKG done which came back normal. I get tired easily. I have not used any medications other than birth control pills. Do you recommend I get further tests done, as my WBC and ANC are still on the lower end?

Kindly advise.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

Apart from the low WBC (white blood cell) count, low neutrophils, and high LDL (low-density lipoprotein) levels, you do not have any other abnormalities.

The common causes of leukopenia (low WBC count) are:

1. Decreased production in the bone marrow.

2. Increased destruction outside the bone marrow.

3. Infections.

4. Nutritional deficiencies.

A low WBC count with low neutrophils predisposes one to an increased risk of acquiring infections. In some cases, chronic stress can also be a cause. Therefore, it would be a good idea to have a peripheral blood smear study and exclude vitamin deficiencies, especially vitamin B12 and folic acid deficiencies. You might need further tests if there are specific findings on your peripheral blood smear.

I hope this helps.

Thank you.