Patient's Query
Hello doctor,
I had raised ALT (alanine transaminase) to 49 units per liter a few months back, and after a month the value was 109 units per liter. Now, it is 19 units per liter. I was asked to take various liver screening autoimmune blood tests, hepatitis B and C screen tests, and GGT (gamma-glutamyl transferase) and LFT, and all the test reports were normal. Ultrasound scans, which I took a few months back, were normal. But the recent one was a little different. I have attached the report to this. I do not understand what it means about the liver. Is my liver abnormal? Can you please explain it to me? I am confused.
Kindly help.
Thank you.
Hello,
Welcome to icliniq.com.
I read your query and can understand your concern.
I have seen your reports (attachment removed to protect the patient’s identity), and here are my suggestions:
1. This is a non-specific ultrasound finding and has less clinical significance, especially in the presence of normal LFTs (liver function tests), good serum albumin levels, negative hepatitis B/C, and an autoimmune profile.
2. Ultrasound is an operator-dependent modality; radiologist experience and expertise matter a lot, and reports can vary a bit.
3. You had three ultrasounds within the last four months, which we usually do not recommend, especially in the absence of some very specific reason for re-imaging.
4. This report can be a variation due to the experience and expertise of radiologists.
5. As previously discussed, I would suggest going for a fibroscan at some good, renowned hospital, and all your concerns will be cleared. The mild coarse texture of the liver can be related to the normal aging process.
I hope this helps.
Thank you, and take care.
Regards.
Patient's Query
Hello doctor,
Thank you for the reply.
The report is also non-specific, and it mentions, "This is a non-specific ultrasound finding, and these features have been associated with possible metabolic or infective changes." No gallstones are present."
It says about possible metabolic changes. Does this mean I should check my cholesterol? Infective changes - It could not be as I had the hepatitis screening. Also, is this indicative of fatty liver?
I understand the variations you mentioned, but still, there is a difference between the other two reports, and part of me is thinking if something has developed since my first report. But was it missed in the second scan and picked up in the recent one? What does this sound like to you?
I will go through a fibroscan, but it is going to mean I have to pay for it, as it is unlikely the doctor will give it, or there might be a delay.
Please help.
Thank you.
Hello,
Welcome back to icliniq.com.
I understand your concern.
Metabolic is not specific for cholesterol, but fatty liver can come under metabolic syndrome. In that case, LFTs (liver function tests) are already normal. Your concerns are valid, and it has created significant confusion at your end; I can understand it. Liver change echo texture is a slow process; it cannot be affected within weeks. There are two possibilities: one is that this report is over-reported, and the other is that previous reports are under-reported. To clear this confusion, fibroscan is the best investigation to consider.
I think your general physician should consider this because, for you, it is causing significant health anxiety.
I hope this helps.
Kindly follow up if you have more concerns.
Thank you.
Patient's Query
Hello doctor,
Thank you for your reply.
With fibroscan, I will speak to my GP about this. I have also attached my older reports, if you would not mind checking this, please?
Also, what does this mean, metabolic is not specific to cholesterol, but yes, fatty liver can come under metabolic syndrome. In that case, LFTs (liver function tests) are already normal. Doctor, what do you mean by "in that case, LFTs are already normal"?
Please help.
Thank you.
Hello,
Welcome back to icliniq.com.
Thanks for asking again. So, LFTs are already normal, which means if I assume a fatty liver, there is still no damage to the liver in the presence of normal liver function tests. I think this is an over-reported ultrasound and I think it is not serious.
My professional experience says, we usually ignore such non-specific findings and counsel patients accordingly, and in case of health anxiety, we suggest a solution, like in this case, fibroscan. In such a short time, I am not expecting any changes in liver parenchyma.
I hope this clarifies your doubts.
Kindly follow up if you have more concerns.
Thank you.
Patient's Query
Hello doctor,
Thank you for your reply.
I will just move on from this and disregard it then? What do you mean by counseling patients accordingly? Finally, can a cholesterol of 5.6 play a role in this scan? Or is it unrelated to these findings? And if there are fatty liver early signs, can this be reversed and fully back to normal with lifestyle changes?
Please help.
Thank you.
Hello,
Welcome to icliniq.com.
I can understand your concern.
Yes, please move on, as this is triggering your health anxiety by overthinking about this non-specific finding. A fibroscan is the best test to find out your liver status, which would be within normal limits as per my clinical assessment and your blood reports.
Counseling means talking to the patients regarding their concerns, and we are discussing them right now. Cholesterol will not cause a direct coarse echo texture of the liver in the absence of fatty liver. Your liver function tests are already back to normal; this liver texture confusion is going on, which can be sorted out by fibroscan.
I hope this clarifies your doubts.
Kindly follow up if you have more concerns.
Thank you.
Patient's Query
Hello doctor,
Thank you for your reply.
So I have nothing to worry about? And do I move on from this? I do not have any liver problems, as indicated by my results; I am fine. The fibroscan you recommended, for my confusion, but is it necessary?
Cholesterol will not induce direct coarse echo texture of the liver in the absence of fatty liver, as you said. Is it possible that the ultrasound report does not specifically mention fatty liver?
The above ones are my final questions. And also no further action now for me?
Kindly suggest.
Thank you.
Hello,
Welcome back to icliniq.com.
Yes, nothing to worry about at the moment with normal liver function tests. A fibroscan is necessary both for your confusion and to document the exact liver status at the moment (specific, not like non-specific as your ultrasound mentioned). No fatty liver on ultrasound, so cholesterol is more risk for cardiac issues rather than liver, especially in the absence of fatty liver. No further action is needed, in fact, three ultrasounds within three months are too much too, without any direct indication. A fibroscan is necessary, because of current confusion and your concerns.
I hope this clarifies your doubts.
Kindly follow up if you have more concerns.
Thank you.
Patient's Query
Hello doctor,
Thank you for answering me. So a fibroscan is required for my confusion? Otherwise, may I leave it for now?
Please suggest.
Thankyou.
Hello,
Welcome back to icliniq.com.
Yes, you are right.
Take care.
Patient's Query
Hello doctor,
Okay, thanks, doctor.
So, nothing is wrong with my liver, right?
Please suggest.
Hello,
Welcome back to icliniq.com.
Yes, nothing is wrong.
Take care.
Patient's Query
Hello doctor,
Thank you for all of your help. I appreciate your expertise as a liver specialist.
Thankyou.
Hello,
Welcome back to icliniq.com.
You are most welcome.
Wishing you excellent health.
Kind regards.
Patient's Query
Hello doctor,
Thank you for your reply.
Sorry it's me again. Apologies to bother you. I just wanted to double check something with you. I have attached my ultrasound liver scan here. This report was six moths back.
It is a normal scan. My question is, can you expect any changes from then to now even with a very bad diet? Not alcohol.
This older scan I am confident was right. But want to check if any developments can potentially happen between these six months? Especially when my ALT (alanine aminotransferase) went higher to 109.
Also, this older scan, the attached scan was done by a consultant radiologist, where my new scan was by a sonographer, does this make a difference? I just want to be sure, can I rely on the older scan? Or could there be chances of changes?
Kindly suggest.
Thank you.
Hello,
Welcome back to icliniq.com.
I can understand your concern.
1) No, I do not expect any liver parenchymal changes within three to four months, even with ALT 109 in between. This ALT was not that high and the liver has a huge potential to self heal, so it is not expected that it would change echo texture within a few months like this.
2) Ultrasound is a dependent modality so I will go with consultant assessment rather than sonographer assessment.
3) One very clear thing is your health anxiety, and you are worried just because of one comment that there is a non-specific liver finding.
Do not overthink, this will induce further health anxiety, just relax, your ALT is normal now and you have an option of fibroscan to confirm your liver status.
I hope this clarifies your doubts.
Kindly follow up if you have more concerns.
Thank you.
Patient's Query
Hello,
Thank you doctor. It is just that my own doctor is not giving any direction. So you are saying my liver is normal and just to let it go now and move on?
Please suggest.
Thankyou.
Hello,
Welcome to icliniq.com.
So,
1) Yes, your liver is normal and I will consider consultant radiologist opinion above then a sonographer.
2) I would suggest to move on, take normal diet, avoid unnecessary medicine, regular walk and stop overthinking about this.
3) You can do two things. Get a fibroscan if possible, or, repeat ultrasound by consultant radiologist after around two to three months.
This is a simple plan. This is what we do during our routine clinical practices.
I hope this clarifies your doubts.
Kindly follow up if you have more concerns.
Thank you.
Patient's Query
Hello doctor,
Thank you doctor for the options.
Do you think fibroscan will come back normal for me in my situation? Or unsure? Also, if I do not do the ultrasound in a few months (as I am trying for a baby). Would that be okay? I mean is there a necessity? Or are you putting the options for my peace of mind? Thanks once again doctor. I will just move on from this and get on with my life.
Thankyou.
Hello,
Welcome back to icliniq.com.
I can understand your concern.
So,
1) In your case, fibroscan will be normal or it will show F0 to F1 level of stiffness which is pretty normal at age above 30 years (nothing specific for you). No major issues are expected as your liver function tests were ok with good serum Albumin levels and no old, or chronic history of liver disease.
2) That is totally fine, if you will try for baby, best wishes for that too. During pregnancy, we always check LFTs (liver function test) as a normal protocol so it will be checked by default, nothing specific for your to worry.
3) Options are not just for your peace of mind. these are the most logical options being a Hepatologist. Meanwhile, telling you to relax and nothing to worry is important too, to avoid unnecessary health anxiety.
4) Yes you should move on and enjoy your life.
I hope this clarifies your doubts.
Kindly follow up if you have more concerns.
Thank you.
Patient's Query
Hello doctor,
Thank you so much doctor I appreciate your advice. Finally, to confirm, with a normal older scan, it is possible for there to be a change in the liver recently? Can things change in a few months?
Please suggest.
Thankyou.
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Answered byDr. Ghulam Fareed
Medically reviewed byiCliniq medical review team
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