My LFT is raised for a year with recent AST, ALP, and GGT showing 200. Please help.

Question

Hi doctor,

I am 23 years old. It has been more than a year, and my liver function test result remains high. I have been tested for hepatitis A, B, C, E, and autoimmune hepatitis, but the results all came out negative. My doctor told me to take blood tests regularly. But it has been almost a year now, and the result still remains high. The lowest result so far I get is AST 90. But my latest liver function test result shows my AST, ALP, and GGT are all 200+. May I get any advice on this?

I did not take any medication or consume any alcohol, but the result still came out high. I am so worried about that.

Please help.

Answer 1

Hello,

Welcome to icliniq.com.

I can imagine that you must be very concerned about your persistent elevation of the liver enzymes. As you already have viral etiologies excluded, this is the time to look for other things that could lead to persistent elevation of the liver enzymes. Notably Wilson's disease, alpha-antitrypsin deficiency, hemochromatosis, and autoimmune hepatitis type II. I want you to upload all your previous investigations, ultrasound reports if done, and any other testing that you have performed in the past two years.

I also suggest you get the following blood tests, which would help us exclude the above possibilities. It is possible that you have some testing already, and I do not want you to repeat it, but do upload the reports so I can see those. Secondly, despite you having a viral screening that showed nothing abnormal, there are certain other tests, like Hb core total, that can detect occult or latent infections and the cause of your raised enzyme levels.

Since the investigation may cause you significant cost, it is a possible alternative that you can discuss with me in detail, as we can shrink some of those testings by closely inquiring about those causes in history before getting tested. I am sure we would reach a conclusive diagnosis based on the relevant information you provide and after investigations.

I hope this helps.