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What causes negative LH surge and spotting while on DHEA?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 41 years old and trying to conceive for 13 months. My AMH is 4.3 and FSH is 8.2. Thyroid and uterus are all normal. I was put on IVF short protocol before six months and managed to get only one egg and IUI failed. I fell pregnant naturally after three months but had a miscarriage at 6.5 weeks. Period came normally after 28 days of D and C.

I then started DHEA on the next cd1 and continued with Cd10 and pregnacare. On cd10 I started Inositol and folate supplement. I have been testing for LH surge since this cd7 and no positive yet. I have on and off right side dull ache similar to ovulation time. I am now cd19 with no surge but spotted yesterday and now have some red bleeding. I am confused if this is my period or ovulatory connected and or related to DHEA. I know I should have tested my DHEA level prior. I will keep testing for surge but I suspect this is a very early period. I am taking supplements to improve my egg quality prior to IVF next year. Please advise.

Answered by Dr. Sameer Kumar

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

If there has been no LH (luteinizing hormone) surge positivity in the kit and you have spotted, it simply means that this is irregular shedding where the endometrium has grown till mid-cycle and is unsupported in the absence of progesterone which is released post ovulation by corpus luteum. So ovulation is pending naturally and this is endometrium breaking and bleeding in the absence of progesterone which marks the start of the secretory phase of menstrual cycle.

Patient's Query

Thank you doctor,

I still have the right side dull ache and have more than spotting but it is not like a proper period. Can I still ovulate or is it too late this cycle? Why has this irregular bleeding occurred? The ache, blood and date make me suspect a rupture of a follicle. Is this possible? I had this pain for more than a few days. Is this just an early period? Is it worth getting an internal scan? I was concerned whether DHEA had impacted me in this way. Please advise.

Answered by Dr. Sameer Kumar

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

As you are on your cd19 with no LH surge, it is likely that you may not have ovulated yet. However, the confirmation can be achieved only by a transvaginal ultrasound which if delineates a collapsed follicle then it shall confirm a rupture and release of an ovum with some fluid in the pouch of Douglas on ultrasound.

You have to understand that menses are always a progesterone withdrawal response in the second phase of the cycle and hence in the absence of ovulation (without LH surge) is not termed as menses. The bleed in the shedding of the endometrium are mostly darkish brown in color and not actually bright red as in menstrual flow.

Ultrasound shall also tell you about the endometrial thickness, which if is more than 8mm, and the presence of blood in utero indicates proliferative endometrium which has not been stabilized by progesterone yet (in the absence of ovulation as corpus luteum secretes progesterone after follicle rupture). So in short, you can continue testing for LH surge for three more days and if still no surge and the bleeding increases, then you can consider this as a failed cycle.

Medically reviewed by iCliniq medical review team
Published At November 21, 2019
Reviewed At June 3, 2024

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

This doctor is not available for online consultations on the platform anymore.

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