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What can cause knee pain with swelling?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 27 years old. I have had knee pain in both legs, and it has been painful alternately for the past one and a half years. Pain starts with swelling around the knee and lasts for three to four hours, and the pain will occur at least once in one to two months.

I feel like pinching with a needle in the feet. I also get back pain in the early morning. I have consulted a specialist, and he told me to do the attached laboratory tests. I have an ASO titer of 800 IU/mL, and I do not have any tiredness, headache, fever, history of jaundice, joint pain, etc.

Please help.

Answered by Dr. Narayanasamy Senduran

Education:

MD Physician

Professional Bio:

Dr. Narayanasamy Senduran is a Family Physician who completed his MD Physician from Astrakhan State Medical University, Russia, in 2011. He has 12 years of clinical experience and is well-versed in English, Russian, Tamil, and Telugu. He is practicing in Chennai, Tamil Nadu.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I have noted your complaints and also gone through the reports carefully (attachment removed to protect patient identity). You seem to have a preceding streptococcal A infection. I would like to know if you had any history of skin or throat infection left untreated or treated ineffectively in the recent past. Elevated ASO (anti-streptolysin O) titer, arthritis pain, and swelling of both knees make me think of rheumatic fever.

I suggest you do an echocardiogram (echo) to rule out any heart involvement and follow up every one or two months. Also, I suggest you do the WBC (white blood cells), ESR - erythrocyte sedimentation rate, C-reactive protein (CRP), ASO titer, and anti-DNAse B titer to be monitored every two weeks. Secondary prophylaxis to prevent recurrent rheumatic fever episodes and rheumatic heart disease, if diagnosed.

The treatment plan is as follows: NSAIDs (nonsteroidal anti-inflammatory drugs) like Celecoxib 200 mg, Piroxicam 20 mg twice a day. It can help to reduce the symptoms of pain and swelling.

Also, I suggest you take shots of Benzathine Penicillin G 1.2 million units every four weeks or a month, for the next three years. Also, you seem to have mild anemia, for which I suggest you take the capsule Livogen-Z (combination of ferrous fumarate and folic acid) twice a day for one month. Consult your specialist doctor, discuss with him or her, and take the medicine with consent. Physical examination and detailed clinical history play a vital role. Hence, I suggest you visit a rheumatologist or general physician in person for the betterment of your health.

Thank you and take care.

Regards

Medically reviewed by iCliniq medical review team
Published At June 28, 2016
Reviewed At June 10, 2026

Education:

MD Physician

Professional Bio:

Dr. Narayanasamy Senduran is a Family Physician who completed his MD Physician from Astrakhan State Medical University, Russia, in 2011. He has 12 years of clinical experience and is well-versed in English, Russian, Tamil, and Telugu. He is practicing in Chennai, Tamil Nadu.

This doctor is not available for online consultations on the platform anymore.

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Knee Pain with Swelling: Rheumatic Fever Awareness Builder

Knee pain and swelling?

Five quick questions help you understand potential causes of your knee pain and swelling, and when to talk to a doctor.

For guidance only, not a diagnosis. Consult a healthcare professional for personalized advice.

Education:

MD Physician

Professional Bio:

Dr. Narayanasamy Senduran is a Family Physician who completed his MD Physician from Astrakhan State Medical University, Russia, in 2011. He has 12 years of clinical experience and is well-versed in English, Russian, Tamil, and Telugu. He is practicing in Chennai, Tamil Nadu.

This doctor is not available for online consultations on the platform anymore.

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