How to manage inflammatory breast cancer?

Question

Hello doctor,

My 44-year-old sister has inflammatory breast cancer (stage 3). Her breast became suddenly red and swollen, but three doctors missed it, saying it was an infection. Now, we are worried about ourselves and our mom. Is this type of cancer hereditary? The symptoms seem so different from regular breast cancer. Should we get various kinds of screening? Also, her treatment plan seems more intense than what I usually hear about. Is that normal for this type?

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

Hereditary risks-

1. Inflammatory breast cancer and genetics: While there is a genetic component to some breast cancers, inflammatory breast cancer (IBC) is not typically associated with a strong family history or specific genetic mutations.

2. BRCA mutations: However, it is essential to note that some people with IBC may carry BRCA (breast cancer gene)1 or BRCA2 mutations, which increase the risk of breast and ovarian cancer.

Screening recommendations-

1. Mammography and ultrasound: Annual mammography and ultrasound screenings are recommended for you and your mom, starting at age 40.

2. MRI (magnetic resonance imaging) screening: If your sister carries a BRCA mutation or you have a strong family history, consider annual MRI screenings in addition to mammography and ultrasound.

3. Clinical breast exams: Regular clinical breast exams by a healthcare professional are also crucial.

Inflammatory breast cancer symptoms-

1. Distinct symptoms: IBC symptoms can be mistaken for infections, as in your sister's case. Common symptoms include:

- Rapid breast enlargement.

- Redness and swelling.

- Warmth or tenderness.

- Itching or ridging.

- Nipple inversion.

Treatment intensity-

1. Aggressive treatment: IBC is an aggressive subtype requiring intensive treatment. Your sister's treatment plan may include:

- Neoadjuvant chemotherapy.

- Surgery (mastectomy).

- Radiation therapy.

- Targeted therapy or hormone therapy (if applicable).

To better understand your sister's treatment plan and provide guidance, I need more information about her ongoing medications and treatment plan.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.