How to control the progression of hypothalamic obesity?

Question

Hi doctor,

I have a cousin who was recently told he has something called hypothalamic obesity. The doctors mentioned it has to do with the brain, and it is different from regular weight gain. He has been struggling to manage his weight, despite trying various diets and exercise routines. From what I have seen, his appetite is through the roof, and he is getting frustrated because nothing seems to help. Are there any treatments that work better for this kind of thing, especially since it is more about hormones than lifestyle? And is there a way to prevent it from getting worse?

Kindly help.

Answer 1

Hi,

Welcome to icliniq.com.

I read your query and can understand your concern.

The hypothalamus, a part of the brain, plays a crucial role in regulating hunger, appetite, and energy expenditure. Hypothalamic obesity occurs after an injury to the hypothalamus, which can disrupt the balance of hormones that regulate hunger and satiety. As a result, individuals may experience an increased appetite and reduced ability to burn calories, making weight management difficult.

There is no specific medication approved solely for hypothalamic obesity, but appetite suppressants or medications that affect satiety (satisfaction or fullness) signals may help. Must consult with an endocrinologist, and addressing hormonal imbalances can help.

In cases where weight gain is severe, bariatric surgery might be a consideration. But it may not be suitable for everyone.

Take a dietitian's opinion and minimize excessive calorie intake.
Regular Physical Activity can help.
Regular check-ups with the doctor and regular checking for blood glucose, lipid levels, and blood pressure may help.

Revert with the answer to assist further.

Thank you and take care.

Regards.