How to control hypertension and prevent kidney disease?

Question

Hello doctor,

I am a 36-year-old woman. My kidney is failing. I have high levels of metanephrines. My blood pressure is high and sometimes it is low. Also, I experience anxiety, tiredness, headache, and bloating. I am not sure whether I have water retention. I went for investigations three years back when I started having severe headaches, and my blood pressure was over 190/90 mm of Hg. I have undergone a 24-hour urine test, urine analysis, CT, and ultrasound scan. I have attached the test reports for your reference. Currently, I am using Exforge HCT, Amlodipine, Spironolactone, Topomax, and Hydrochlorothiazide. For the last six months, I have stopped working and started a low-protein diet. Also, I have begun using CBG-CBD oils. My medications and their dosages have been altered multiple times in the last two years. What is the reason for my kidney failure?

Kindly advise.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern and would be happy to help. I have reviewed your reports (attachments removed to protect the patient's identity). The metanephrines and normetanephrines are not high enough to suspect a pheochromocytoma or paraganglioma. Also, you have fewer chances of having a clinically significant adrenal tumor. Untreated or uncontrolled high blood pressure can affect your kidneys, and currently, your kidney function is stable as your blood pressure is controlled. I suggest you continue using the same medicines for hypertension.

I hope this helps.

Kindly revert in case of further questions.

Thank you.

Answer 2

Hello,

Welcome back to icliniq.com.

You have a few values of normetanephrine and metanephrine above the normal range. The circumstances and medicines you are taking and how the sample was collected can also affect the results. However, none of the results are high enough to say you have a catecholamine-secreting tumor. Therefore your chances of having a pheochromocytoma or paraganglioma are significantly less. The lack of a visible tumor also adds more evidence. I suggest you repeat the tests under ideal circumstances.

I hope this helps.

Thank you.