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Is HIV possible after negative test results?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I and my partner went through an HIV 1 and 2 test five months back. Both of us tested negative. This month we had unprotected sex. I did not have sex in between and upon asking my partner, he too said that he had no sex with anyone else. He does not do any drugs and stays with parents. However, I panicked and went to the doctor and insisted upon PEP. Four days back, my partner went through a CMIA test and was negative (0.27). I think he is clean. However, I am still scared. In this situation, do you think I might be in HIV risk?

Please help.

Thank you.

Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I have reviewed your query, and here is my advice. Your partner is HIV negative with a CMIA (chemiluminescent microparticle immunoassay, a laboratory technique used to detect and measure substances such as hormones, proteins, or antibodies in blood or other fluids) test. But this test can effectively exclude HIV (Human Immunodeficiency Virus is a virus that attacks the body'simmune system, specifically the CD4 cells (T cells), which help fight infections. If left untreated, HIV can lead to AIDS Acquired Immunodeficiency Syndrome) after six weeks of exposure. Mostly, your partner might be right, and if you believe him, then do not worry about HIV. But if you have a doubt regarding any form of exposure, then again after six weeks, a repeat test is needed. As per my opinion, although the chance of HIV is less, you should get investigated with HIV after six weeks of exposure to effectively rule out HIV. (By CMIA or fourth-generation ELISA test, Enzyme-Linked Immunosorbent Assay). It is a widely used laboratory test to detect antibodies, antigens, proteins, or hormones.

I hope this helps.

Kindly revert if there is any query.

Thank you.

Patient's Query

Hi doctor,

Thanks a lot. I will go for a CMIA test in the second week of next month. I hope it would be clean.

Please help.

Thank you.

Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

Yes, investigate with the CMIA test or fourth-generation ELISA test after six weeks of exposure. Hope it would be negative.

I hope this helps.

Kindly revert if there is any query.

Thank you.

Medically reviewed by Dr. K. Shobana
Published At October 21, 2018
Reviewed At November 25, 2025

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

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Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

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