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What is the importance of bioavailable testosterone?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My husband was found to have elevated testosterone (over 1009 - the limit of the test), but normal LH and other hormones. A testicular ultrasound was normal. What are the possible diagnoses? Could Graves' disease cause this?

Answered by Dr. Bindiya Thakkar

Hi,

Welcome to icliniq.com.

Graves' disease does not cause high testosterone. I have a few questions.

1. What medicine he is taking now? What is his age?

2. Is he on any supplements? What was the bioavailable testosterone?

Patient's Query

Thank you doctor,

He is 30 years old. He is not on any medication or supplement. We have not got the free testosterone results yet.

Answered by Dr. Bindiya Thakkar

Hi,

Welcome back to icliniq.com.

The first and foremost thing is to rule out exogenous exposure. If that is not the case, then wait for bioavailable levels. If high, then I would recommend doing another set, but at 8 AM along with TSH (thyroid-stimulating hormone), cortisol, ACTH (adrenocorticotropic hormone), LH (Luteinizing hormone) and FSH (follicle stimulating hormone). Is there any high blood pressure or diabetes or cholesterol or fractures? Did you observe any change in his behavior like aggression? Also, who is evaluating him?

Patient's Query

Hi doctor,

An endocrinologist at this point. Do you suggest any potential diagnosis other than an adrenal tumor? What will the bioavailable tell us? No high blood pressure, diabetes, fractures, high cholesterol or behavior changes. Also, definitely no exogenous sources.

Answered by Dr. Bindiya Thakkar

Hi,

Welcome back to icliniq.com.

Bioavailable testosterone will tell you true or active testosterone levels. Total level can be falsely high as its measurement depends on the protein in the body. I would consider pituitary too, as a source.

Answered by

Dr. Bindiya Thakkar

Medically reviewed byiCliniq medical review team

Published At August 27, 2016
Reviewed AtMay 31, 2023

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Bindiya Thakkar

Dr. Bindiya Thakkar

Endocrinology

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