Patient's Query
Hi doctor,
My platelets were 468 last month, and I repeated another full CBC. Everything else was fine, but my platelets were still 463 a month later. Is this something to worry about?
I have fatty liver grade 1 and mild IBS. I also had a Coronavirus infection two months ago. Currently, I am on multivitamins.
Kindly suggest.
Hello,
Welcome to icliniq.com.
Elevated platelets indicate the following conditions:
Elevated platelets are seen in iron deficiency anemia, infections, inflammation, drug-induced, and very rarely it could be a part of essential thrombocythemia. To rule out the causes of secondary thrombocytosis. If all causes are excluded, get JAK2 (Janus kinase 2), Exon 12, and CALR mutations tested.
Even in primary thrombocytosis, also called essential thrombocythemia, these mutations are negative frequently. In cases of secondary thrombocytosis, the treatment of elevated platelets is to treat the cause. In primary thrombocythemia, if JAK2 is negative, the treatment is cytoreductive therapy by hydroxyurea. The goal is to keep platelets below 1000 thousand.
Thrombolytic drugs such as Aspirin, Clopidogrel, and Warfarin are also a part of therapy. For JAK2 positive patients, Ruxolitinib tablets are given in a dose of 5 to 15 mg per day. Another option is IFN alpha in low dose (45 ug/week) in both JAK2 positive or negative cases. CALR positive cases show superior results on this model. It could take years to cure the disease. This is not a life-threatening disease unless thromboembolism involves the heart, lungs, or/and brain. Sometimes, the first manifestation of the disease is thromboembolic events.
Your platelets are touching the borderline. Just follow up every six months and keep taking Aspirin 75 mg/day.
I hope this helps you.
Thank you.
Patient's Query
Hello doctor,
Thank you for your reply.
What is it in my case?
Kindly suggest.
Hello,
Welcome back to icliniq.com.
Please get CRP (C-reactive protein), ESR (erythrocyte sedimentation rate), ferritin, ANA (anti-nuclear antibodies) by immunofluorescence test to rule out the possible causes. If these tests are inconclusive, no need to investigate further. Just follow up that count.
I hope this helps.
Thank you.
Same symptoms don't mean you have the same problem. Consult a doctor now!
Related Questions
What can cause high platelet and low Hb?
I have high platelet levels with migraine. Kindly interpret my MRI report.
What are the reasons for high platelet count?
Is it normal to have high platelet count in a high blood pressure patient?
Can you list the drugs incompatible with Quetiapine and Lamotrigine?
What are the side effects of Tizanidine?
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.