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How to manage C-section bleeding in hemophilia patients?

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Patient's Query

Hello doctor,

I am 36 weeks pregnant and a confirmed carrier of hemophilia (factor VIII level at 32 percent). Amniocentesis confirmed that my baby boy has hemophilia. I am now in preterm labor and require an urgent C-section, but I am extremely worried about the risk of bleeding.

  • What protocol should be followed?
  • Is factor replacement necessary?

Please help.

Thank you.

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

Your situation is high-risk, and a specialized delivery plan is essential to ensure the safety of both you and your baby. A multidisciplinary team, including obstetrics (focuses on pregnancy, childbirth, and postpartum care), hematology (deals with blood disorders, including anemia and clotting conditions), and neonatology (specializes in the medical care of newborns, especially premature or ill infants), should be involved in your care.

Managing your bleeding risk includes:

  1. Factor VIII infusion - Levels should be raised to at least 50 to 100 percent before surgery.

  2. Antifibrinolytics - IV (intravenous) Tranexamic acid can help prevent excessive bleeding. Kindly consult your doctor and take medicines accordingly.

  3. Postpartum monitoring - Careful observation for postpartum hemorrhage or PPH (excessive bleeding after childbirth) is crucial.

  4. Factor replacement post-surgery - Continued infusions for 24 to 72 hours may be needed.

  5. Anesthesia considerations - If factor levels are low, avoid spinal or epidural anesthesia (regional anesthesia) due to the risk of spinal hematoma (a blood accumulation in the spinal canal). General anesthesia may be safer.

Managing your baby’s hemophilia includes:

  1. Avoid vacuum or forceps - These increase bleeding risks.

  2. Delayed cord clamping - Helps boost the baby’s blood volume.

  3. Neonatal hematology consultation - Immediate evaluation is necessary.

  4. Factor VIII replacement - If needed, it should be given promptly.

  5. Monitoring for bleeding - Head ultrasound to check for intracranial hemorrhage (bleeding inside the brain).

Ensure factor VIII concentrate and blood products are available before surgery. Plan for NICU (neonatal intensive care unit) support, as the baby will need close postnatal monitoring.

I hope this helps.

Kindly revert so I can assist you further.

Thank you.

Medically reviewed byiCliniq medical review team

Published At March 17, 2025
Reviewed AtMay 19, 2026

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