Patient's Query
Hello doctor,
I would like to know about drug-induced gigantomastia in women. I am currently taking Aripiprazole, which has caused weight gain and hormonal changes. Specifically, the hormone that binds testosterone is low. Additionally, I have rheumatoid arthritis, an autoimmune condition that may be relevant. My previous medical history includes starting Aripiprazole for schizoaffective disorder when I was 32 years old and weighed 147 pounds. After four to five years of taking the drug, I now weigh 196 pounds and have an increased breast size, which continues to grow. Based on these symptoms, I suspect I have drug-induced gigantomastia. I underwent a prolactin test, and the results came back normal and within the expected range.
Kindly help.
Hello,
Thanks for trusting us with your health care.
I have gone through your history and understand your concerns. You are right; there is a small risk of gynecomastia with antipsychotic drugs as they have prolactin-sparing properties, which can lead to hyperprolactinemia (higher level of prolactin hormone) and gynecomastia (enlargement of breast tissue). It is important to note that other hormonal imbalances can also cause gynecomastia.
I hope this has helped you. Thank you.
Patient's Query
Hello doctor,
Thank you for the reply.
My prolactin levels are normal on this drug, but the hormone that binds to testosterone is abnormally low. Are you saying that this could also affect the situation?
Hello,
Welcome back to icliniq.com
If your testosterone-binding hormone is low, it may also affect the condition and cause gynecomastia. Kindly attach your reports below. Generally, these drugs can cause hyperprolactinemia.
I hope this has helped you. Thank you.
Was this conversation helpful?
Answered byDr. Richa Agarwal
Medically reviewed byiCliniq medical review team
Same symptoms don't mean you have the same problem. Consult a doctor now!
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.