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Is surgery or radiation advised for a Gleason score of 8?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My biopsy report confirmed cancer with a Gleason score of 8. My urologist said this is aggressive but still localized. Should I prioritize surgery, radiation, or systemic treatments like hormone therapy? How do these options compare in terms of long-term survival and quality of life?

Kindly help.

Thank you.

Hello,

Welcome to icliniq.com.

I can understand your concern.

I am sorry to hear about your diagnosis. To provide a well-informed opinion, I would need more details about your condition. This includes a detailed history of your symptoms (if any) or whether the cancer was diagnosed incidentally.

Additionally, I would need the results of your biopsy, MRI, or PET (magnetic resonance imaging, positron emission tomography) scan, along with information about your overall fitness levels.

For localized prostate cancer and holistic cancer, systemic therapy is not typically required and is reserved for metastatic disease. Both radiation therapy and surgery have their advantages and drawbacks, and the decision depends on your clinical details and personal preferences.

Once you provide the necessary details, I will do my best to assist and share detailed information sheets and my recommendations.

Thank you.

Medically reviewed byiCliniq medical review team

Published At January 17, 2025
Reviewed AtApril 16, 2026

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