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Am I experiencing a hormonal imbalance after menopause at 64?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am 64 and in the postmenopausal stage. I had a hormone blood test and my testosterone was very low, less than 5. My vitamin D was low and my Estradiol was 73. I started to take supplements, all-natural like DHEA, vitamin D, HGH and Smilax. I just got tested again and my vitamin D is fine.

But, my Estradiol is even higher and my testosterone is 114. Now, two days before, I took the test while on Smilax which I know has its effect on testosterone level. I am mostly worried about estradiol and ovarian cancer.

Please help.

Thank you.
Answered by Dr. Anantha Bhaskar Ramalingam

Education:

MBBS

Professional Bio:

Dr. Anantha Bhaskar Ramalingam is a well-experienced General Physician with 30 years of clinical experience. He completed his MBBS from Madras University in 1993. He then completed his MD in Diabetology from Stanley Medical College in 1997. He is well-specialized in Diabetology and Endocrinology. He is currently working in Chennai, Tamil Nadu.

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Hi,

Welcome to icliniq.com.

Your estrogen level should be low at the postmenopausal stage. But, your estrogen level is similar to the level of normal reproductive years. Estrogen helps bone but carries the risk of breast cancer, and uterine (endometrial) cancer. Estrogen therapy in the postmenopausal period also carries the potential risk of ovarian cancer. DHEA (Dehydroepiandrosterone sulfate) can help to increase energy and sex drive (libido) but not definite. DHEA is converted in the body to testosterone.

I hope this helps.

Thank you.

Patient's Query

Hi doctor,

Thank you for your reply.

I do not feel my question was answered.

  1. I am asking if having high estrogen without any estrogen replacement therapy and high DHEA may in and of itself be an indication of ovarian cancer?
  2. Is the high testosterone combined with the high estrogen, an indication of possible ovarian cancer?

Please help.

Thank you.

Answered by Dr. Anantha Bhaskar Ramalingam

Education:

MBBS

Professional Bio:

Dr. Anantha Bhaskar Ramalingam is a well-experienced General Physician with 30 years of clinical experience. He completed his MBBS from Madras University in 1993. He then completed his MD in Diabetology from Stanley Medical College in 1997. He is well-specialized in Diabetology and Endocrinology. He is currently working in Chennai, Tamil Nadu.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Hi,

Welcome back to icliniq.com.

Only estrogen replacement in the form of hormone replacement therapy is known to be associated with ovarian cancer. I am not aware of any studies showing the body's own secretion of estrogen (high or low) associated with ovarian cancer.

Ovarian cancer cells express the estrogen receptors so that they can be stimulated to grow by estrogen. I am not aware of any studies showing a correlation between blood testosterone level and risk of ovarian cancer.

Please feel free to ask if further clarification is required.

Thank you.

Medically reviewed by Dr. Hemalatha
Published At February 4, 2020
Reviewed At February 26, 2026

Education:

MBBS

Professional Bio:

Dr. Anantha Bhaskar Ramalingam is a well-experienced General Physician with 30 years of clinical experience. He completed his MBBS from Madras University in 1993. He then completed his MD in Diabetology from Stanley Medical College in 1997. He is well-specialized in Diabetology and Endocrinology. He is currently working in Chennai, Tamil Nadu.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. Hemalatha is a dedicated Dental Surgeon with expertise in preventive, restorative, and cosmetic dental care. She is passionate about promoting oral health and creating personalized treatment plans to suit each patient’s needs. Her clinical approach emphasizes patient comfort, precision, and long-term dental wellness, ensuring a positive and reassuring experience for every individual under her care.

This doctor is not available for online consultations on the platform anymore.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Anantha Bhaskar Ramalingam
Dr. Anantha Bhaskar Ramalingam

Endocrinology

Consult this doctor

Education:

MBBS

Professional Bio:

Dr. Anantha Bhaskar Ramalingam is a well-experienced General Physician with 30 years of clinical experience. He completed his MBBS from Madras University in 1993. He then completed his MD in Diabetology from Stanley Medical College in 1997. He is well-specialized in Diabetology and Endocrinology. He is currently working in Chennai, Tamil Nadu.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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