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Can one have mitochondrial embryo donation at 44 years?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am considering mitochondrial embryo donation. However, prior to doing so, I am wondering about a home hormonal balancing option as I found online. Which do you suggest for attempting first?

I am 44 years old with an AMH of .5 ng/mL, six follicles located in the ultrasound, an FSH level of 10 mIU/mL or under, and an endometrium lining of 356 mm.

Thanks in advance.
Answered by Dr. Sameer Kumar

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

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Hello,

Welcome to icliniq.com.

In your case, medical treatment for raising AMH (anti-mullerian hormone test) levels can be offered before opting for an IVF (in-vitro fertilization) or ICSI (intracytoplasmic sperm injection) procedure. Also please share the online hormonal balancing option which you have come across.

I hope I have answered your question.

Let me know if I can assist you further.

Regards.

Patient's Query

Thank you doctor,

Thanks for the reply. As for raising AMH level, would you be referring to HCG injections? I heard that Clomid does not offer much assistance for my age group.

As for the online hormonal balancing option, it is offered by a fertility concern. I attached a screenshot of the hormones claimed for the test and balance out.

I was initially planning for IVF or mitochondrial transfer procedures as I was told by experts that my age group and outlook are grim. But, then, I was wondering if those procedures would even be helpful for someone of my age group.

Kindly help.

Answered by Dr. Sameer Kumar

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Hello,

Welcome back to icliniq.com.

Thanks for the follow-up. If you have been menstruating regularly as on date, then AMH can be improved after reviewing your DHEAS (dehydroepiandrosterone sulfate) levels. HCG injections have been used for oocyte priming before IVF or ICSI procedure but they do not affect AMH levels.

In your case, DHEAS with Vitamin D3 supplementation and NOVELON tablet (Ethinyl estradiol with Desogestrel) for continuous two cycles should be offered and then AMH levels can be rechecked. But DHEAS levels and 17OHP (17-hydroxyprogesterone) levels are mandatory to be learned before the initiation of therapy.

I hope I have answered your question.

Let me know if I can assist you further.

Regards.

Patient's Query

Thank you doctor,

Thanks so much for the extremely helpful replies. I have one further question for you. If those suggestions fail, do you believe that mitochondrial transfer procedures actually assist a female in my age group? Or, is it overhyped in certain corners of the world?

I think that this procedure is done for those females under 40 years old.

Thanks again.

Answered by Dr. Sameer Kumar

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

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Consult other doctors in the same speciality

Hi,

Welcome back to icliniq.com.

Hello, I would like to state that mitochondrial DNA (deoxyribonucleic acid) transfer is considered an option for those women who have mitochondrial DNA disease, which is being passed on to her by her mother and so forth running in generations.

AMH levels or ovarian reserve pertaining to age group has nothing to do with it. Unless you have a mitochondrial DNA disease and suffered from multiple miscarriages or non-viable pregnancies because of it, then it can be an option.

But if your oocyte quality is fine or improved by medication then you can opt for an ICSI procedure with your own oocyte rather than opting for a donor egg and then an ICSI procedure (intracytoplasmic sperm injection). If you do not succeed with your own egg, then opt for a donor egg and IVF procedure.

I hope I have answered your question.

Let me know if I can assist you further.

Regards.

Medically reviewed by Dr. K. Shobana
Published At November 13, 2021
Reviewed At March 9, 2026

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

This doctor is not available for online consultations on the platform anymore.

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Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Sameer Kumar
Dr. Sameer Kumar

Obstetrics and Gynecology

Consult this doctor

Education:

MBBS

Professional Bio:

Dr. Sameer Kumar is a highly qualified Obstetrician and Gynecologist and Infertility specialist with more than two decades of clinical experience. He has completed his postgraduate training in Obstetrics and Gynecology and also specializes in infertility management. Dr. Kumar is dedicated to women’s health, offering expert care in pregnancy, reproductive health, and fertility treatments. His patient-centered approach combines medical expertise with compassionate support to ensure the best outcomes for his patients. Note: If you don't want go opt for IVF and spend lakhs, then you must contact me as i specialize in medical infertility treatment for both male and female. Results have been really encouraging and statistics speak for itself, about 2000 couples helped and avoided IVF.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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